Hypoxia triggers hypoxia-inducible factor (HIF). Not only hypoxia triggers downstream HIF target genes for transcription, as intermittent hyperoxia also possesses similar capabilities, suggesting that fluctuations in oxygen availability may be equally important for inducing HIF transcription. This review describes some of the mechanisms, whereby intermittent hyperbaric hyperoxia may explain some of the observations during hyperbaric oxygen therapy such as enhanced wound healing, angiogenesis and tissue healing, and concludes that oxidative stress enhances certain antibiotics in infection control.
View Article and Find Full Text PDFA 55-year-old woman was hospitalised due to sudden redness and swelling around the left eye as well as malaise. Prior to hospitalisation, the patient was treated with antibiotics because of a dental infection. The patient was admitted to the hospital for more than three weeks and received intravenous antibiotics, which was changed several times due to treatment failure.
View Article and Find Full Text PDFBackground: To present a rare case of a 2-year-old girl with neurofibromatosis type 1 (NF1) who presented with ptosis of the right upper eyelid along with a tumor in the eyelid.
Methods: A magnetic resonance imaging scan of the orbit revealed a solid tumor located extraconally at the site of the right lacrimal gland. A transcranial orbitotomy was performed.