A Retrospective Analysis of Pinnaplasty Outcomes: The Welsh Experience.

Prominent ears (PEs) are the most frequent congenital external ear deformity, occurring in ∼5% of the population. Although the deformity does not usually cause functional difficulties, it can significantly affect the patient's psychological and social health. The authors aim to present the Welsh experience of pinnaplasty, reviewing our outcomes and complications.

Neonatal ear splinting for congenital ear deformities.

Splinting of ears in neonates to correct the congenital auricular deformities has been well described. Despite being a non-invasive technique and having a potential to prevent need for correctional surgery, it's up-take across the UK has been poor. This study evaluates the outcomes of neonatal ear splinting for congenital ear deformities from a regional ear splinting service.

A not-so-sweet diagnosis - leukocytoclastic vasculitis masquerading as squamous cell carcinoma.

Leukocytoclastic vasculitis (LCV) is a rare small-vessel vasculitis characterised by neutrophilic inflammation of post-capillary venules. Incidence varies from 3 to 4.5 per 100 000 people per year.

These umbilical lesions weren't granulomas after all.

Consider a VID remnant as part of the differential diagnosis for any patient who has what appears to be a granulomatous umbilical lesion. Order ultrasonography to evaluate a suspected VID, especially for lesions that fail to respond to 2 or 3 silver nitrate treatments. Surgical excision of a VID remnant is usually curative.

The use of a cell-free chondroinductive implant in a child with massive cartilage loss of the talus after an open fracture dislocation of the ankle: a case report.

Background: We present a case report of a 3-year-old girl who sustained a severe open fracture dislocation of her talus with complete loss of full-thickness articular cartilage and subchondral bone over 80% of the talar dome. At presentation there was an extensive soft tissue defect including absent anterior joint capsule. She required a free anterolateral thigh flap to reconstruct this defect.

The origins and regulation of tissue tension: identification of collagen tension-fixation process in vitro.

The absence of a controllable in vitro model of soft tissue remodeling is a major impediment, limiting our understanding of collagen pathologies, tissue repair and engineering. Using 3D fibroblast-collagen lattice model, we have quantified changes in matrix tension and material properties following remodeling by blockade of cell-generated tension with cytochalasin D. This demonstrated a time-dependent shortening of the collagen network, progressively stabilized into a built-in tension within the matrix.