Growth Dynamics and Survival of BT-1, an Important Model Organism for the Citrus Huanglongbing Pathogen " Liberibacter asiaticus".

is the only cultured member of its genus, which includes the devastating plant pathogen " Liberibacter asiaticus," associated with citrus greening/Huanglongbing (HLB). has a larger genome and greater metabolic flexibility than " Liberibacter asiaticus" and the other uncultured plant-pathogenic species, and it is currently the best model organism available for these pathogens. grows slowly and dies rapidly under current culture protocols and this extreme fastidiousness makes it challenging to study.

Enhanced disinfection of bacterial populations by nutrient and antibiotic challenge timing.

Several difficult to treat illnesses like tuberculosis, chronic pneumonia, and inner ear infections are caused by tolerant bacteria enmeshed in a biofilm. Bacterial tolerance can be genotypic (resistance-i.e.

Predictive Computer Models for Biofilm Detachment Properties in Pseudomonas aeruginosa.

Microbial biofilm communities are protected against environmental extremes or clearance by antimicrobial agents or the host immune response. They also serve as a site from which microbial populations search for new niches by dispersion via single planktonic cells or by detachment by protected biofilm aggregates that, until recently, were thought to become single cells ready for attachment. Mathematically modeling these events has provided investigators with testable hypotheses for further study.

Biofilms and infectious diseases: biology to mathematics and back again.

There has been tremendous growth in biofilm research in the past three decades. This growth has been reflected in development of a wide variety of experimental, clinical, and theoretical techniques fostered by our increased knowledge. Keeping the theoretical developments abreast of the experimental advancements and ensuring that the theoretical results are disseminated to the experimental and clinical community is a major challenge.