Cognitive and behavioral outcomes among seizure-controlled children with partial epilepsy on antiepileptic drug monotherapy.

The objective of this study was to assess cognitive performance and behavioral symptoms in a sample of children diagnosed with partial epilepsy who were seizure controlled on AED monotherapy for one year. Ninety-eight seizure-controlled children on AED monotherapy were included in this study. Specific AEDs examined included topiramate, divalproex sodium, lamotrigine, levetiracetam, and oxcarbazepine.

Concurrent Validity of New Subscale Scores for the Booklet Category Test.

The Booklet Category Test (BCT) is a neuropsychological test of cognitive dysfunction that provides only one overall error score indicative of global impairment. It does not, however, delineate specific domains that might be impaired. The aim of this study is to concurrently validate 13 new BCT subscales using legacy instruments in patients with nonpenetrating traumatic brain injury (TBI).

Reliability of the Clinical Dementia Rating with a traumatic brain injury population: a preliminary study.

This study examined the inter-rater reliability (IRR) of the Clinical Dementia Rating (CDR) for patients with traumatic brain injury (TBI). The CDR is a commonly used rating of impairment, but there has been no research examining its utility in patients with TBI. It was hypothesized that the CDR would have good IRR when used with patients with TBI.

Frontal lobe epilepsy in children and adolescents: a preliminary neuropsychological assessment of executive function.

Although research on adults with frontal lobe epilepsy (FLE) has increased in recent years, delays in frontal lobe development preclude the generalization of these findings to children. This study compared children with FLE with typically developing children on cognitive and executive tests. Additionally, the differences between children with early and late seizure onset were explored.

Are the indices of the RBANS sufficient for differentiating Alzheimer's disease and subcortical vascular dementia?

Alzheimer's disease (AD) and subcortical vascular dementia (SVaD) are among the most prevalent dementias and they often show specific patterns of cognitive dysfunction. This study examined whether differences exist between groups on the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) that could assist with differential diagnosis. The examiners utilized the NINCDS-ADRDA and the NINDS-AIREN criteria to identify 39 probable AD and 29 probable SVaD patients.

The neurometric-quantitative electroencephalogram as a predictor for psychopharmacological treatment: an investigation of clinical utility.

A retrospective validation study of the Neurometric method of the Quantitative Electroencephalogram (QEEG) in predicting response to psychotropic medication was conducted. The clinical outcomes of 2 groups of patients were compared: those patients prescribed medication regimens that were concordant with the QEEG predictors vs. those whose medication regimens were discordant with the QEEG predictors.

The category test perseveration, loss of set, and memory scales: three new scales and their relationship to executive functioning measures.

The Category Test (CT) is a neuropsychological measure that taps into multiple domains of complex reasoning but yields a single error score, limiting the use of the test. In this study, three new CT scales were developed to assess specific aspects of executive dysfunction: Perseveration, Failure to Maintain Cognitive Set, and Inability to Recall and Re-Initiate Past Behavior. The relationship of these scales to well-established neuropsychological measures was examined in head-injured individuals and schizophrenia patients.