Is there a relationship between impaired median nerve excursion and carpal tunnel syndrome? A systematic review.

Study Design: Systematic review.

Introduction: It is accepted that the etiology of carpal tunnel syndrome (CTS) is multifactorial. One of the most commonly accepted etiologic factors for CTS is compromise of the kinematic behavior and excursion of the median nerve.

Flexgrepps--flexible greedy peptide pool search: computation of near-optimal sets of degenerate polypeptides for antigenic screening.

Although synthesizing and utilizing individual peptides and DNA primers has become relatively inexpensive, massively parallel probing and next-generation sequencing approaches have dramatically increased the number of molecules that can be subjected to screening; this, in turn, requires vast numbers of peptides and therefore results in significant expenses. To alleviate this issue, pools of related molecules are often used to downselect prior to testing individual sequences. A computational selection process to create pools of related sequences at large scale has not been reported for peptides.

The transcriptome of Mycobacterium tuberculosis.

In this review, we summarize the present understanding of the Mycobacterium tuberculosis transcriptome and catalog both experimentally verified findings and computationally derived predictions. We also provide a new analysis for a range of discoveries by comparing the results of previously independent research papers. Bringing these data together and improving their accessibility should help catalyze further discoveries.