Publications by authors named "Nicholson S Chadwick"
Elbow arthroplasty is increasing in popularity and can be used to treat many conditions, such as trauma, primary and secondary osteoarthritis, inflammatory arthritis, and osteonecrosis. Total elbow arthroplasty (TEA) is reserved for patients with severe symptoms refractory to more conservative management. In addition to TEA, hemi-arthroplasty, interposition arthroplasty, and resection arthroplasty also play roles in the management of elbow pain.
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- * This surgery is indicated for conditions like arthritis, fractures, and severe rotator cuff issues, with different types of arthroplasties available, including total, hemi-, and reverse shoulder arthroplasties, each having specific uses and risks.
- * Imaging techniques like X-rays, MRIs, and CT scans are crucial for evaluating the shoulder before and after surgery, helping identify any complications and assessing the condition of the shoulder post-operatively.
Article Synopsis
- Exposure to tobacco carcinogens is the leading cause of lung cancer, but even heavy smokers only have about a 10% lifetime risk of developing it, highlighting the need for better risk assessment methods.
- Current screening methods based on age and smoking history have limited effectiveness, and researchers explored the use of hypermutable microsatellites in buccal cells to evaluate mutational load as a risk indicator.
- However, the study found no significant link between smoking status or lung cancer case status and mutation frequency, indicating that while mutation load increases with age, it does not differ significantly between those who develop lung cancer and those who do not, questioning the reliability of these microsatellite mutations as biomarkers for lung cancer risk.