Priming lymphocyte responsiveness and differential T cell signaling in pediatric IBD patients with use.

The prevalence of inflammatory bowel disease (IBD) has increased dramatically in recent years, particularly in pediatric populations. Successful remission with current therapies is limited and often transient, leading patients to seek alternative therapies for symptom relief, including the use of medical marijuana (). However, chronic cannabis use among IBD patients is associated with increased risk for surgical interventions.