Publications by authors named "Nicholas Wallingford"
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Synopsis of recent research by authors named "Nicholas Wallingford"
- Nicholas Wallingford's research primarily focuses on the regulatory mechanisms involved in food intake and their implications for neurodegenerative diseases, with particular emphasis on the roles of neuropeptides and extracellular matrix components in these processes.
- Key findings include the identification of prolylcarboxypeptidase as a regulator of alpha-MSH activity, influencing food intake and body fat composition in rodent models, as well as the impact of zonisamide in preventing weight gain associated with olanzapine treatment in rats.
- Additionally, Wallingford's studies explore the accumulation of hyaluronan in demyelinated lesions related to multiple sclerosis, as well as the role of CD44 in oligodendrocyte functions and its contribution to demyelination and dysmyelination, advancing understanding of neuroinflammatory and neurodegenerative conditions.