Publications by authors named "Nicholas Semenza"
Article Synopsis
- Clinical trials indicate that cervical disc arthroplasty (CDA) is a safe, effective alternative to anterior cervical discectomy and fusion (ACDF) for treating cervical degenerative disc disease, with various CDA devices available that differ in constraint levels.
- The study utilized a systematic review and network meta-analysis comparing outcomes of ACDF versus CDA across different constraint levels in a sizable patient sample over at least two years.
- Results showed that both semiconstrained and unconstrained CDA types had a lower risk of adjacent segment degeneration and subsequent surgeries compared to ACDF; semiconstrained CDA also had a lower risk of reoperation at the index level.
Study Design: Single-center retrospective cohort.
Purpose: To compare surgical outcomes of patients based on lumbar drain variables relating to output and duration.
Overview Of Literature: The use of drains following lumbar spine surgery, specifically with respect to hospital readmission, postoperative hematoma, postoperative anemia, and surgical site infections, has been controversial.
Article Synopsis
- The Masquelet technique is rarely used in hand cases with osteomyelitis, but it was applied to a patient facing amputation due to traumatic bone loss.
- After the patient refused amputation, the technique involved two stages: initial surgical debridement and antibiotic spacer placement, followed by grafting and joint fusion eight weeks later.
- Ultimately, the procedure successfully resolved the osteomyelitis and preserved the finger, achieving bone healing and joint stability.
Study Design: Retrospective cohort study.
Objective: The aim was to investigate the clinical relevance of preoperative caudal adjacent segment degeneration (ASD) in patients undergoing isolated L4-5 fusion to determine a threshold of degeneration at which a primary L4-S1 fusion would be warranted.
Summary Of Background Data: Increased motion and biomechanical forces across the adjacent caudal segment in isolated L4-L5 fusion leads to concerns regarding the increased incidence of revision surgery because of the development of ASD.
Study Design: Retrospective cohort study.
Objective: The aim was to compare the outcomes of patients with incompletely corrected cervical deformity against those without deformity following short-segment anterior cervical decompression and fusion for clinically significant radiculopathy or myelopathy.
Summary Of Background Data: Cervical deformity has increasingly been recognized as a driver of disability and has been linked to worse patient-reported outcomes measures (PROMs) after surgery.
Article Synopsis
- This study is a retrospective cohort analysis aimed at assessing outcomes for patients with cervical degenerative spondylolisthesis who underwent anterior cervical discectomy and fusion.
- It compared results between patients who had surgery performed at the same level as the spondylolisthesis (SL) and those who did not (DL), evaluating demographic data, surgical details, and patient-reported outcomes.
- While both groups showed significant improvement in most measures post-surgery, the SL group experienced poorer preoperative alignment and notably did not see improvements in mental health scores after surgery.
Study Design: This study is a retrospective case control.
Objectives: This study aims to determine whether cervical degenerative spondylolisthesis (DS) is associated with increased baseline neck/arm pain and inferior health quality states compared to a similar population without DS.
Methods: Patient demographics, pre-operative radiographs, and baseline PROMs were reviewed for 315 patients undergoing anterior cervical decompression and fusion (ACDF) with at least 1 year of follow-up.
Objective: Spinal decompression with or without fusion is one of the most commonly performed procedures in spine surgery. However, there is limited evidence on the effect of discharge environment on outcomes after surgery. The purpose of this study is to identify the effects of discharge disposition setting on clinical outcomes after spine surgery.
View Article and Find Full Text PDFBackground: Acute spinal cord injury (ASCI) is a devastating event that can have a profound impact on the lives of patients and their families. While no definitive medical treatment exists, the role of methylprednisolone (MP) in the management of ASCI and other spinal cord pathologies has been investigated in depth; however, its use remains contentious. While MP initially showed promise in the efficacy of ASCI treatment, more recent studies have questioned its use citing numerous systemic adverse effects.
View Article and Find Full Text PDFPurpose: High-rate, persistent criminal offending has substantial negative health consequences. This study examines how criminal offending trajectories during adolescence influence the risk of food insecurity in early adulthood.
Methods: The study uses four waves of the National Longitudinal Study of Adolescent to Adult Health to determine the association between criminal offending trajectory membership and food insecurity.