Publications by authors named "Nicholas Mp Clarke"

Article Synopsis
  • Developmental dysplasia of the hip (DDH) is a frequent congenital disorder that may require surgical intervention, but there's uncertainty about the timing of surgery and its effects on complications like avascular necrosis (AVN).
  • A study aims to compare early versus delayed surgical treatment in children aged 12 weeks to 13 months with DDH, focusing on the incidence of AVN and the need for further surgery after five years.
  • The trial involves a random assignment of participants to receive either early or delayed surgery and includes health economic assessments to analyze costs associated with both approaches.
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Background: There is little current consensus regarding the route or duration of antibiotic treatment for acute osteomyelitis (OM) and septic arthritis (SA) in children.

Objective: To assess the overall feasibility and inform the design of a future randomised controlled trial (RCT) to reduce the duration of intravenous (i.v.

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