Publications by authors named "Nicholas Kirwen"
Article Synopsis
- Men with low-risk prostate cancer are increasingly choosing active surveillance (AS) instead of immediate treatment, but many later switch to active treatment.
- A multi-institutional study analyzed genetic data from over 5,000 prostate cancer patients who opted for AS to identify genetic factors that might predict those likely to switch to treatment.
- The study found 18 genetic variants related to the decision to change treatment and established a link between certain genetic risk scores and the likelihood of converting from AS to active treatment, suggesting that genetics could personalize monitoring and treatment decisions for these patients.
Background: A variety of penile rehabilitation (PR) therapies are available to improve post-prostatectomy erectile dysfunction (ED) with mixed results. It is uncertain how adherent men are to PR therapies. The aim of this study is to determine adherence to and identify barriers to PR treatment.
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