Publications by authors named "Nicholas Kendall"
Article Synopsis
- The study evaluated the efficacy and safety of pRESET stent-retriever systems for treating large vessel occlusion acute ischemic stroke through a systematic review and meta-analysis of relevant studies until March 2024.
- A total of 1140 participants were analyzed, revealing that pRESET systems achieved a notable first-passing effect rate of 53.4% and a high rate of successful thrombolysis (90.41%).
- The findings suggest that the pRESET device has a comparable safety and efficacy profile to existing mechanical thrombectomy devices, with a 90-day mortality rate of 15.1% and a post-intervention hemorrhage rate of 28.6%.
Aim: To address substantial gaps in the literature on neuroanatomical variations in females with fragile X syndrome (FXS).
Method: Surface-based modeling techniques were applied to the magnetic resonance imaging of 45 females with FXS (mean age = 10 years 9 months, range 6 years-16 years 4 months, SD = 2 years 9 months) and 33 age-matched and developmentally matched females without FXS to elucidate differences in cortical gray matter volume, surface area, and thickness. Gray matter volumes in subcortical regions were examined to ascertain differences in subcortical volume.
Since 2007, research groups are mandated by the Food and Drug Administration Amendments Act (FDAAA) to report clinical trial findings to ClinicalTrials.gov within 12 months of trial completion. This observational study aims to analyze compliance data of stroke-related randomized controlled trials subject to these mandates.
View Article and Find Full Text PDFBackground: Upper limb disorders (ULDs) are clinically challenging and responsible for considerable work loss. There is a need to determine effective approaches for their management.
Aim: To determine evidence-based management strategies for work-relevant ULDs and explore whether a biopsychosocial approach is appropriate.
An investigation into GPs with high patient mortality rates: a retrospective study.
J Public Health (Oxf)
September 2005
Background: As part of the work of the Shipman Inquiry, five general practitioners (GPs) in West Sussex were identified as having excessively high mortality rates. The aim of this study was to identify reasons for the higher-than-expected mortality rates of these five GPs.
Methods: A retrospective analysis was made of routine mortality and patient registration data from primary-care practices in West Sussex, and the case notes of deceased patients were reviewed.
Objectives: The objective is to study how the staff who purchase health care services for a large national government accident-compensation system seek information on treatment effectiveness, how they assess the quality of that information, whether they question the information sources they choose, and how familiar they are with the key concepts of evidence-based health care (EBHC).
Method: Staff (22 out of 34) of the health purchasing division of the New Zealand Accident Compensation Corporation (NZ ACC) were interviewed using eight preformatted questions to which they could provide open and multiple answers. Responses were subsequently codified into typologies for quantitative analysis.