Characterizing missed identifications and errors in latent fingerprint comparisons using eye-tracking data.

Latent fingerprint examiners sometimes come to different conclusions when comparing fingerprints, and eye-gaze behavior may help explain these outcomes. missed identifications (missed IDs) are inconclusive, exclusion, or No Value determinations reached when the consensus of other examiners is an identification. To determine the relation between examiner behavior and missed IDs, we collected eye-gaze data from 121 latent print examiners as they completed a total 1444 difficult (latent-exemplar) comparisons.

The Impact of Microenvironmental Heterogeneity on the Evolution of Drug Resistance in Cancer Cells.

Therapeutic resistance arises as a result of evolutionary processes driven by dynamic feedback between a heterogeneous cell population and environmental selective pressures. Previous studies have suggested that mutations conferring resistance to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKI) in non-small-cell lung cancer (NSCLC) cells lower the fitness of resistant cells relative to drug-sensitive cells in a drug-free environment. Here, we hypothesize that the local tumor microenvironment could influence the magnitude and directionality of the selective effect, both in the presence and absence of a drug.