Publications by authors named "Nicholas Ferrari"

Article Synopsis
  • A synthetic glycolate metabolic pathway introduced in potatoes resulted in increased tuber biomass over two growing seasons without compromising tuber quality.
  • Transformed potato plants showed significantly enhanced daily carbon assimilation and photosynthetic capacity, especially after early season heatwaves, demonstrating resilience against heat stress.
  • The study suggests that this modified pathway could be a viable strategy for improving potato yields amid the challenges posed by increased heatwave events due to global warming.
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Oxygenic photosynthetic organisms use Photosystem II (PSII) to oxidize water and reduce plastoquinone. Here, we review the mechanisms by which PSII is assembled and turned over in the model green alga . This species has been used to make key discoveries in PSII research due to its metabolic flexibility and amenability to genetic approaches.

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Obesity is associated with various metabolic disorders, such as insulin resistance and adipose tissue inflammation (ATM), characterized by macrophage infiltration into adipose cells. This study presents a new Drosophila model to investigate the mechanisms underlying these obesity-related pathologies. We employed genetic manipulation to reduce ecdysone levels to prolong the larval stage.

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Obesity is a global health concern associated with various metabolic disorders including insulin resistance and adipose tissue inflammation characterized by adipose tissue macrophage (ATM) infiltration. In this study, we present a novel model to investigate the mechanisms underlying ATM infiltration and its association with obesity-related pathologies. Furthermore, we demonstrate the therapeutic potential of attenuating Eiger/TNFα signaling to ameliorate insulin resistance and ATM.

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Article Synopsis
  • * Traditional research on plant metabolism often occurs in controlled settings, which may not accurately reflect how plants respond to environmental stressors that affect photosynthetic efficiency.
  • * A new fast screening method using chlorophyll fluorescence analysis helps identify genes involved in photorespiration by monitoring how abiotic stress impacts photosynthetic efficiency in Arabidopsis thaliana mutants.
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