Publications by authors named "Nicholas D'Ardenne"
Article Synopsis
- Gain-of-function mutations in the CTNNB1 gene, responsible for β-catenin production, are present in 25-30% of hepatocellular carcinomas (HCC), significantly influencing treatment resistance and drug sensitivity.
- A study involving 134 HCC patients aimed to create a non-invasive imaging model to assess β-catenin activation, as liver biopsies pose risks.
- The developed model demonstrated improved predictive accuracy for β-catenin activation when combining qualitative LI-RADS descriptors and quantitative radiomics features, suggesting strong potential for precision medicine strategies in treating HCC.
Hybrid imaging with F-18 fludeoxyglucose positron emission tomography/magnetic resonance imaging (FDG PET/MRI) has increasing clinical applications supplementing conventional ultrasound, CT, and MRI imaging as well as hybrid PET/CT imaging in assessing cervical, endometrial, and ovarian cancer. This article summarizes the existing literature and discusses the emerging role of hybrid PET/MRI in gynecologic malignancies. Thus, far, the published literature on the applications of FDG PET/MRI shows that it can have a significant impact on patient management by improving the staging of the cancers compared with PET/CT, influencing clinical decision and treatment strategy.
View Article and Find Full Text PDFEvans et al. (2016) showed that radiologists can classify the mammograms as normal or abnormal at above-chance levels after a 250-ms exposure. Our study documents a similar gist signal in digital breast tomosynthesis (DBT) images.
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