Publications by authors named "Nicholas Champion"

Article Synopsis
  • The study investigates how frailty and malnutrition affect surgery outcomes in older adults with breast cancer, focusing on patients over 60 using specific indices to assess these factors.
  • A review of cases from 2000-2016 found that older patients with certain risk factors had worse 5-year survival rates, yet malnutrition did not significantly impact survival compared to their healthier counterparts.
  • The findings suggest that the modified frailty index (MFI) is a valuable tool in predicting long-term survival in patients aged 80 and older, highlighting its importance in preoperative assessments.
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Article Synopsis
  • Breast cancer is the most common cancer among women, with statistics showing about 1 in 8 women will develop an invasive form during their lives.
  • The review focuses on dendritic cell vaccines, a type of immunotherapy that has shown promise in improving patient outcomes by enhancing the immune response against cancer cells.
  • It discusses how these vaccines can target specific drivers of cancer development and emphasizes the need for effective vaccine design to successfully prevent breast cancer progression.
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Background: SmartClip is a food and drug administration-approved, electromagnetic chip (EMC) localization system that provides three-dimensional navigation for the excision of soft tissue lesions. The purpose of this study was to analyze the accuracy and feasibility of EMC radiologic and surgical localization for benign and malignant breast lesions.

Patients And Methods: An institutional review board-approved, single institution, prospective study from October 2020 to September 2022 of 38 women undergoing breast conserving surgery with EMC localization of a single lesion > 5 mm on mammogram (MMG) or ultrasound (US) imaging.

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A symptomatic adrenal mass diagnosed during pregnancy is a rare clinical scenario. Two primary considerations are the timing of intervention and determining the appropriate surgical approach. Here, we present the case of a young female patient with flank pain, whom on diagnostic imaging, was found to have a large cystic adrenal mass.

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When endoscopy is performed for acute GI bleeding, therapeutic endoscopic procedures are infrequently required (only 6% of cases). We sought to determine the natural history of GI hemorrhage in patients who have undergone therapeutic endoscopy. We queried our hospital database for inpatients with acute GI bleeding who underwent therapeutic endoscopy between 2015 and 2017.

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