Publications by authors named "Nicholas C Sangala"

People with end-stage kidney disease (ESKD) often exhibit impaired cardiac structure and function, which may contribute to poor exercise capacity. This study used multimodal exercise testing to investigate the central and peripheral mechanisms of exercise limitation in adults with ESKD, also comparing in-centre hemodialysis (ICHD) to home hemodialysis (HHD). Seventeen adults (55.

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Background: Although kidney transplantation is the best treatment for kidney failure, scarce research has examined its effects on physical activity, physical function and quality of life.

Objectives: To investigate the experiences of a group of adults living with advanced kidney disease focusing on quality of life, physical activity and function and to see how findings differ in a group of kidney transplant recipients.

Approach: Individual semi-structured interviews were conducted with adults with advanced kidney disease (n = 10; 70.

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Background: When people with chronic kidney disease reach kidney failure, renal replacement therapy is usually required to improve symptoms and maintain life. Although in-centre haemodialysis is most commonly used for this purpose, other forms of dialysis are available, including home haemodialysis and peritoneal dialysis.

Objectives: We aimed to explore the experiences of adults living with chronic kidney disease who were either approaching the need for dialysis or had reached kidney failure and were receiving a form of dialysis.

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Article Synopsis
  • Early in the COVID-19 pandemic, individuals with end-stage renal disease (ESRD) were deemed highly vulnerable and advised to stay home, leading to significant changes in their healthcare delivery through telemedicine.
  • * A study explored the impacts of these restrictions on physical activity, wellbeing, and quality of life among adults undergoing home hemodialysis (HHD) and in-center hemodialysis (ICHD) in the UK.
  • * Results indicated that the pandemic negatively affected physical activity and wellbeing, but participants expressed support for telemedicine, highlighting its role in promoting independence and satisfaction in patient care.
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