Publications by authors named "Nicholas C Figueroa"
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Synopsis of recent research by authors named "Nicholas C Figueroa"
- Nicholas C. Figueroa's research primarily focuses on the development of inhibitors for the JAK2 tyrosine kinase, which is crucial in the study of hematological disorders, such as myeloproliferative neoplasms.
- His work involves the use of structure-based virtual screening to identify novel compounds, including a benzothiophene-derived inhibitor named A46, aimed at suppressing aberrant JAK2 signaling.
- Figueroa highlights the therapeutic potential of effective JAK2 inhibitors, emphasizing their significance in treating conditions associated with somatic mutations in the JAK2 gene found in various hematological malignancies.