Towards routine, city-scale accessibility metrics: Graph theoretic interpretations of pedestrian access using personalized pedestrian network analysis.

A wide range of analytical methods applied to urban systems address the modeling of pedestrian behavior. These include methods for multimodal trip service areas, access to businesses and public services, diverse metrics of "walkability", and the interpretation of location data. Infrastructure performance metrics in particular are an increasingly important means by which to understand and provide services to an urbanizing population.

Cell-Cell Communication in Yeast Using Auxin Biosynthesis and Auxin Responsive CRISPR Transcription Factors.

An engineering framework for synthetic multicellular systems requires a programmable means of cell-cell communication. Such a communication system would enable complex behaviors, such as pattern formation, division of labor in synthetic microbial communities, and improved modularity in synthetic circuits. However, it remains challenging to build synthetic cellular communication systems in eukaryotes due to a lack of molecular modules that are orthogonal to the host machinery, easy to reconfigure, and scalable.