Glycoprotein G-protein Coupled Receptors in Disease: Luteinizing Hormone Receptors and Follicle Stimulating Hormone Receptors.

Signal transduction by luteinizing hormone receptors (LHRs) and follicle-stimulating hormone receptors (FSHRs) is essential for the successful reproduction of human beings. Both receptors and the thyroid-stimulating hormone receptor are members of a subset of G-protein coupled receptors (GPCRs) described as the glycoprotein hormone receptors. Their ligands, follicle-stimulating hormone (FSH) and luteinizing hormone (LH) and a structurally related hormone produced in pregnancy, human chorionic gonadotropin (hCG), are large protein hormones that are extensively glycosylated.

Risk-taking, attitudes toward aggression, and aggressive behavior among rural middle school youth.

This study examined the relationship between risk-taking, general acceptance of aggression (GAA), verbal harassment (VH), and aggressive behavior (AB) in the last 30 days among 1440 seventh- and eighth-grade rural middle school youth. Higher levels of risk-taking predicted higher GAA and VH. Significant interactions for AB indicated that, excepting Black youth, higher risk-taking was related to higher levels of violent behavior.