Publications by authors named "Nicholas Alfonso"

Purpose: Implants in orthopedic trauma and arthroplasty surgery establish a milieu conducive to biofilm formation. Antimicrobial-loaded cements (ABCs) and beads have become popular in treating acute and chronic orthopedic surgery-related infections. The growing incidence of antimicrobial resistance has necessitated the exploration of alternative antibiotic medications.

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  • The study analyzed trends in the economic and utilization of sliding hip screws (SHS) and intramedullary nails (IMN) for treating intertrochanteric femur fractures among Medicare patients over 21 years.
  • It found that the use of IMN significantly increased by 695%, while SHS use dropped by 96% during the same period.
  • Furthermore, physician reimbursements for both methods decreased, with SHS averaging $943.36 and IMN $999.88, indicating a possible cost-effectiveness in choosing SHS when suitable.
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  • - The study assessed the cost-effectiveness of extended postoperative antibiotic prophylaxis (E-PAP) following adult spinal surgeries.
  • - Both types of analysis (stratified and nonstratified) showed E-PAP did not significantly reduce surgical site infections (SSI) compared to standard protocols.
  • - Implementing E-PAP resulted in longer hospital stays and higher costs, with increases of $244.4 for the 72-hour protocol and $309.8 for the >48 hours protocol compared to shorter antibiotic treatments.
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Extensor mechanism (EM) disruption after total knee arthroplasty (TKA) is devastating, especially in cases of re-rupture. A 67-year-old man with diabetes had patellar tendon rupture after revision TKA and then had migration of the bone block after Achilles tendon allograft with bone block (ATBB) augmentation with cerclage. A third reconstruction was performed with open reduction and internal fixation and high-strength braided suture augmentation.

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Objectives: To evaluate patients with tarsometatarsal fractures and dislocations and describe complications and secondary operations.

Design: Retrospective cohort study.

Setting: Level 1 trauma center.

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Objectives: The purpose of this study was to quantify social media usage among Orthopaedic Trauma Association (OTA) members.

Methods: All active OTA members were searched for involvement among common social media platforms. Surgeons were then classified as "active" on any given social media site if they posted within the past 6 months.

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Objectives: To analyze the efficacy of subgroups of various intrawound local antibiotics in reducing the rate of fracture-related infections.

Data Sources And Study Selection: PubMed, MEDLINE via Ovid, Web of Science, Cochrane database, and Science Direct were searched for articles in English on July 5, 2022, and December 15, 2022.

Study Selection: All clinical studies comparing the incidence of fracture-related infection between the administration of prophylactic systemic and topical antibiotics in fracture repair were analyzed.

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Purpose: The purpose of this study was to investigate the amount of saline required to identify a positive traumatic shoulder arthrotomy in a cadaveric model. In addition, intra-articular pressure monitoring was conducted to confirm needle placement and evaluate peak pressure curves prior to capsular failure.

Methods: We conducted a cadaveric study using thirty fresh-frozen upper extremities with maintained glenohumeral joint.

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Objective: To investigate the effect of weight-bearing status on radiographic healing of diaphyseal femur fractures.

Design: Retrospective 1:1 matched cohort study.

Setting: Single-level 1 trauma center.

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Background: Tissue plasminogen activator (tPA) is a thrombolytic agent increasingly being employed for the treatment of acute frostbite. Although tPA has been shown with success to increase digit salvage rates, data on potential complications, including risk of hemorrhage, is limited. As a result, acute trauma is considered a contraindication to use in many institution-based protocols.

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Background: Precontoured quadrilateral surface buttress (PQSB) plates have grown in popularity for acetabular fracture fixation. However, our experience has pushed us to hypothesize that their use as sole means of fixation may cause fracture malreduction. A biomechanical model was created to investigate this theory.

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Objective: To compare the stability of 3 fixation strategies for a transverse acetabular fracture: a reconstruction plate with anterior and posterior column screws (group A); an infrapectineal precontoured quadrilateral surface buttress (iPQSB) plate alone (group B); and an anterior column lag-screw and iPQSB plate (group C).

Methods: A transverse acetabular fracture was created in 18 synthetic hemipelvises. Six were fixed by each of the 3 methods described.

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Objective: The conventional AO buttress screw used for fracture fixation relies on a historic buttress thread design, which is prone to stripping at the bone-implant interface. We hypothesized that a new Bone-Screw-Fastener with an innovative interlocking thread design demonstrates increased resistance to torque stripping forces compared with the buttress screw, without compromising pullout strength.

Methods: A biomechanical model was established in 6 matched pairs of adult human cadaveric tibiae to test torque resistance between the 3.

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Background: Conventional screws used for fracture fixation in orthopedic surgery continue to rely on the historic buttress thread design. While buttress screws generally provide solid resistance against unidirectional axial loading forces, their design suffers from several limitations, as the buttress thread does not adequately resist multiaxial forces. Furthermore, the buttress screw is prone to stripping at the bone-screw interface and can cause microfracturing of the surrounding bone due to its thread design.

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Decades of intensive industrial and agricultural practices as well as rapid urbanization have left communities like Pueblo, Colorado facing potential health threats from pollution of its soils, air, water and food supply. To address such concerns about environmental contamination, we conducted an urban geochemical study of the city of Pueblo to offer insights into the potential chemical hazards in soil and inform priorities for future health studies and population interventions aimed at reducing exposures to inorganic substances. The current study characterizes the environmental landscape of Pueblo in terms of heavy metals, and relates this to population distributions.

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