Publications by authors named "Nicholas A Stewart"
Article Synopsis
- The synthesis and degradation of phospholipids are crucial for the biogenesis of membrane-bound organelles, specifically in regulating their size.
- A lipid degradation pathway was identified that inhibits the expansion of the endoplasmic reticulum (ER) membrane, which is influenced by certain enzymes known as phospholipid diacylglycerol acyltransferases (PDATs).
- The study focused on the yeast PDAT Lro1 and found that its activity can be altered, revealing that active Lro1 not only limits ER membrane expansion but is also regulated by diacylglycerol that affects its distribution and activity.
