2-Aminobenzimidazoles as antibiofilm agents against serovar Typhimurium.

Serovars within the species are some of the most common food and water-borne pathogens worldwide. Some serovars have shown a remarkable ability to persist both inside and outside the human body. serovar Typhi can cause chronic, asymptomatic infection of the human gallbladder.

Meridianin D Analogues Display Antibiofilm Activity against MRSA and Increase Colistin Efficacy in Gram-Negative Bacteria.

In the last 30 years, development of new classes of antibiotics has slowed, increasing the necessity for new options to treat multidrug resistant bacterial infections. Development of antibiotic adjuvants that increase the effectiveness of currently available antibiotics is a promising alternative approach to classical antibiotic development. Reports of the ability of the natural product meridianin D to modulate bacterial behavior have been rare.