Publications by authors named "Nicholas A Cacalano"
Page 1 of 1
Synopsis of recent research by authors named "Nicholas A Cacalano"
- Nicholas A. Cacalano's research primarily focuses on understanding the mechanisms of resistance in prostate cancer, particularly in the context of bone metastases and their interaction with the microenvironment through advanced modeling techniques like patient-derived organoids and xenografts.
- His studies highlight the importance of individualized treatment approaches via three-dimensional organoid cultures that maintain the genomic and functional heterogeneity of tumors, contributing to the development of personalized medicine in cancer therapy.
- Additionally, Cacalano investigates the roles of immune regulation in cancer, particularly through the study of natural killer (NK) cell function and exosomes, showcasing their potential in mediating immune responses and tumor progression.
