Publications by authors named "Nicasius S Tjahjadi"

Aims: Aortic wall stiffening in ascending thoracic aortic aneurysm (aTAA) is common. However, the spatial and temporal relationships between stiffness, aortic size, and growth in aTAA remain unclear.

Methods And Results: In this single-centre retrospective study, we utilized vascular deformation mapping to extract multi-directional aortic motion, aortic distensibility, and aortic growth in a multi-planar fashion from multi-phasic ECG-gated computed tomography angiograms.

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Article Synopsis
  • The study aimed to investigate pre-surgical growth of the aortic arch using vascular deformation mapping (VDM) and how the proximal arch diameter correlates with involvement of a primary ascending aortic aneurysm.
  • The research included 123 patients who had multiple pre-operative CT scans and found that VDM indicated higher growth rates in patients with dilated arches, yet standard diameter measurements often failed to identify significant growth in non-dilated arches.
  • The findings suggest that VDM provides a more accurate assessment of arch involvement than just measuring diameter, which could enhance individualized surgical approaches for patients with ascending thoracic aortic aneurysms.
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Background: Patients with Marfan syndrome (MFS) are at a high risk of type B dissection (TBAD). Aortic growth and elongation have been suggested as risk factors for TBAD. Vascular deformation mapping (VDM) is an image analysis technique for mapping 3D aortic growth on rouine computed tomography angiography (CTA) scans.

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