An efficient smart phone application for wheat crop diseases detection using advanced machine learning.

Globally, agriculture holds significant importance for human food, economic activities, and employment opportunities. Wheat stands out as the most cultivated crop in the farming sector; however, its annual production faces considerable challenges from various diseases. Timely and accurate identification of these wheat plant diseases is crucial to mitigate damage and enhance overall yield.

Comparative Outcomes of Milligan-Morgan (Open) Versus Ferguson (Closed) Hemorrhoidectomy: A Retrospective Study.

Introduction The debate remains unresolved about whether an open (Milligan-Morgan) or closed (Ferguson) approach is superior for hemorrhoidectomy. Advocates from both groups state that each has its own set of advantages and disadvantages. In light of this, we intend to share our experience by comparing the two in terms of their post-operative outcomes.

Evaluation of satisfaction level of Sehat Sahulat Programme among patients and doctors in Lahore and Gujranwala districts, Pakistan.

Objective: To evaluate the satisfaction level of patients and doctors with a health insurance scheme in two districts of Punjab province.

Methods: The analytical, cross-sectional study was conducted from June 2022 to November 2022 at Farooq Hospital West Wood Branch, Akhtar Saeed Trust Hospital, Lahore, Pakistan, and the District Headquarter Hospital, Gujranwala, Pakistan. The sample included doctors and adult inpatients receiving treatment under the Sehat Sahulat Programme.

Integrated geophysical and geospatial techniques for surface and groundwater modeling.

An integrated approach using geophysical and geospatial techniques was employed to model the surface and subsurface water-bearing strata and assess aquifer vulnerability in the Sehnsa town, Kotli district, State of Azad Kashmir, Pakistan. The inadequate scientific studies in the hilly terrain with such complex geological conditions has led to the failure of the boreholes for groundwater extraction. For the evaluation of groundwater potential and subsurface lithology, 30 vertical electrical soundings (VES) stations utilizing the Schlumberger electrode configuration were completed, modeled and analyzed spatially.

Correction: 2-Methyl-4-chlorophenoxyacetic acid (MCPA) sorption and desorption as a function of biochar properties and pyrolysis temperature.

[This corrects the article DOI: 10.1371/journal.pone.

Computationally intelligent real-time security surveillance system in the education sector using deep learning.

Real-time security surveillance and identity matching using face detection and recognition are central research areas within computer vision. The classical facial detection techniques include Haar-like, MTCNN, AdaBoost, and others. These techniques employ template matching and geometric facial features for detecting faces, striving for a balance between detection time and accuracy.

Unlocking the potential of biofilm-forming plant growth-promoting rhizobacteria for growth and yield enhancement in wheat (Triticum aestivum L.).

Plant growth-promoting rhizobacteria (PGPR) boost crop yields and reduce environmental pressures through biofilm formation in natural climates. Recently, biofilm-based root colonization by these microorganisms has emerged as a promising strategy for agricultural enhancement. The current work aims to characterize biofilm-forming rhizobacteria for wheat growth and yield enhancement.

Maternal periodontitis as a risk factor for preterm birth: A cross-sectional study.

Background: Preterm birth is a heterogeneous condition with multiple underlying causes, and periodontal diseases are one of them. Approximately 900000 preterm births are reported in Pakistan each year. Oral infections such as periodontitis during pregnancy are associated with adverse pregnancy outcomes such as low birth weight and preterm births.

Genome sequencing enables diagnosis and treatment of SLC5A6 neuropathy.

The sodium-dependent multivitamin transporter encoded by SLC5A6 is responsible for uptake of biotin, pantothenic acid, and α-lipoic acid. Thirteen individuals from eight families are reported with pathogenic biallelic SLC5A6 variants. Phenotype ranges from multisystem metabolic disorder to childhood-onset peripheral motor neuropathy.

Effects of comorbid conditions and prescribed chronic medications on the treatment plan for chronic hepatitis C infection: A cross-sectional retrospective study.

Background: Chronic hepatitis C (CHC) infection is a potentially life-threatening condition characterized by various complications, including end-stage liver disease and cirrhosis. The mortality rate associated with CHC has been increasing due to the presence of comorbidities and the use of chronic medications. Therefore, the objective of this study was to investigate the impact of these comorbidities and chronic medications on the treatment plan for CHC.

Molecular Analysis of Carbapenem and Aminoglycoside Resistance Genes in Carbapenem-Resistant Clinical Strains: A Challenge for Tertiary Care Hospitals.

Carbapenem-resistant () strains have become a global threat due to their remarkable capability to survive and disseminate successfully by the acquisition of resistance genes. As a result, the treatment strategies have been severely compromised. Due to the insufficient available data regarding resistance from Pakistan, we aimed to investigate the resistance mechanisms of 249 strains by antimicrobial susceptibility testing, polymerase chain reaction for the detection of carbapenemases, aminoglycoside resistance genes, extended-spectrum beta-lactamases (ESBLs), sequence typing and plasmid typing.

Unlocking the interaction of organophosphorus pesticide residues with ecosystem: Toxicity and bioremediation.

Organophosphorus adulteration in the environment creates terrestrial and aquatic pollution. It causes acute and subacute toxicity in plants, humans, insects, and animals. Due to the excessive use of organophosphorus pesticides, there is a need to develop environmentally friendly, economical, and bio-based strategies.

Endovascular therapy versus best medical management for isolated posterior cerebral artery occlusion: A systematic review and meta-analysis.

Background And Purpose: Isolated posterior cerebral artery occlusions (iPCAO) were underrepresented in pivotal randomized clinical trial (RCTs) of endovascular thrombectomy (EVT) in ischemic stroke, and the benefit of EVT in this population is still indeterminate. We performed a systematic review and a meta-analysis to compare the safety and efficacy of EVT compared to best medical management (BMM) in patients with iPCAO.

Methods: We searched Medline/PubMed, Embase, Web of Science, and the Cochrane databases up to May 2023 for eligible studies reporting outcomes of patients with iPCAO treated with EVT or BMM.

2-Methyl-4-chlorophenoxyacetic acid (MCPA) sorption and desorption as a function of biochar properties and pyrolysis temperature.

2-Methyl-4-chlorophenoxyacetic acid (MCPA) is a highly mobile herbicide that is frequently detected in global potable water sources. One potential mitigation strategy is the sorption on biochar to limit harm to unidentified targets. However, irreversible sorption could restrict bioefficacy thereby compromising its usefulness as a vital crop herbicide.

Heavy metals contamination in vegetables irrigated with wastewater: a case study of underdeveloping regions of Pakistan.

Irrigation of food crops with untreated wastewater leads to the accumulation of heavy metals in their edible parts. Exposure to toxic elements through consumption of contaminated vegetables even at very low concentration is becoming a serious problem for human health in many countries. This issue of heavy metals contamination needs great attention especially in Pakistan where irrigation by wastewater has become a common practice in urban and periurban areas.

Development and Characterization of Natural Chromite Coating on Metal Substrate Using the Plasma Spray Process.

Natural materials are gaining interest as coating feedstock because their "quality to cost" ratio is better and they are more environmentally friendly than most of the synthetic ceramics. They give sufficient protection to metal surfaces against harsh conditions such as corrosion, wear, and high temperature. In the current study, chromite mineral was beneficiated and reduced to two different sizes to be used as feedstock material for thermal spray coating.

Functional genomics for curation of variants in telomere biology disorder associated genes: A systematic review.

Purpose: Patients with an underlying telomere biology disorder (TBD) have variable clinical presentations, and they can be challenging to diagnose clinically. A genomic diagnosis for patients presenting with TBD is vital for optimal treatment. Unfortunately, many variants identified during diagnostic testing are variants of uncertain significance.

Prevalence and Molecular Characterization of Methicillin-Resistant from Nasal Specimens: Overcoming MRSA with Silver Nanoparticles and Their Applications.

is a cause of high mortality in humans and therefore it is necessary to prevent its transmission and reduce infections. Our goals in this research were to investigate the frequency of methicillin-resistant (MRSA) in Taif, Saudi Arabia, and assess the relationship between the phenotypic antimicrobial sensitivity patterns and the genes responsible for resistance. In addition, we examined the antimicrobial efficiency and application of silver nanoparticles (AgNPs) against MRSA isolates.

Spatio-temporal change detection of land use and land cover in Malakand Division Khyber Pakhtunkhwa, Pakistan, using remote sensing and geographic information system.

The land use land cover (LULC) change due to the rapidly growing population is a common feature of the urban area. The rapidly growing population in Malakand Division is a greater threat to the LULC of the area due to its negative impact on environment and ecology. This research aims to detect the variations in LULC from 1991 to 2017 in the Malakand Division, Khyber Pakhtunkhwa (KP) province of Pakistan.

Self-initialized active contours for microscopic cell image segmentation.

Level set models are suitable for processing topological changes in different regions of images while performing segmentation. Active contour models require an empirical setting for initial parameters, which is tedious for the end-user. This study proposes an incremental level set model with the automatic initialization of contours based on local and global fitting energies that enable it to capture image regions containing intensity corruption or other light artifacts.

Active power control strategy for wind farms based on power prediction errors distribution considering regional data.

One of the renewable energy resources, wind energy is widely used due to its wide distribution, large reserves, green and clean energy, and it is also an important part of large-scale grid integration. However, wind power has strong randomness, volatility, anti-peaking characteristics, and the problem of low wind power prediction accuracy, which brings serious challenges to the power system. Based on the difference of power prediction error and confidence interval between different new energy power stations, an optimal control strategy for active power of wind farms was proposed.

Thyroid Cancer Screening Using Tumor-Associated DN T Cells as Immunogenomic Markers.

Background: Thyroid nodules are an extremely common entity, and surgery is considered the ultimate diagnostic strategy in those with unclear malignant potential. Unfortunately, strategies aiming to predict the risk of malignancy have inadequate specificity. Our group recently found that the microenvironment of thyroid cancer is characterized by an enhanced immune invasion and activated immune response mediated by double-negative T lymphocytes (DN T) (CD3CD4CD8), which are believed to enable or promote tumorigenesis.

Functional interaction between compound heterozygous TERT mutations causes severe telomere biology disorder.

Telomere biology disorders (TBDs) are a spectrum of multisystem inherited disorders characterized by bone marrow failure, resulting from mutations in the genes encoding telomerase or other proteins involved in maintaining telomere length and integrity. Pathogenicity of variants in these genes can be hard to evaluate, because TBD mutations show highly variable penetrance and genetic anticipation related to inheritance of shorter telomeres with each generation. Thus, detailed functional analysis of newly identified variants is often essential.

Effectiveness of the Graston Technique on Pain and General Foot Health in Patients with Chronic Plantar Fasciitis: A Randomized Clinical Trial.

Background: Chronic plantar fasciitis has been historically treated with conventional physical therapy. The use of the Garston Technique® (GT) is a new intervention for the management of chronic plantar fascitis, but there is lack of evidence in the literature regarding its efficacy.

Study Objective: To evaluate the effectiveness of the GT on pain, foot function and general foot health in patients with plantar fasciitis.