Cepharanthine inhibits the proliferation of glioblastoma cells by blocking the autophagy-lysosomal pathway.

Cepharanthine (CEP) is a Stephania cepharantha-derived bioactive alkaloid that can inhibit the progression of numerous tumors. However, the effects and specific mechanisms of CEP performance in glioblastoma (GBM) remain unclear. Thus, this study focused on exploring the effects of CEP on GBM and clarifying the underlying mechanisms.

Cord blood vitamin E and lipids in infants born small for gestational age.

Unlabelled: Vitamin E is associated with the regulation of lipid metabolism. Our previous study revealed an inverse relationship between birth weight and cord blood vitamin E levels, suggesting a potential link between vitamin E and fetal growth. The aim of this study was to determine the association between vitamin E with fetal growth and lipids.

The function of chemical folic acid in calibration methods and neurodevelopmental disorders.

Functional molecules have been attracting increasing attention in environmental and physiological studies. In particular, folic acid (FA) could be considered a key factor in estimating, adjusting, and making decisions in the treatment of neurodevelopmental disorders. It promotes the general significance and conceptual for considering FA molecular scientific research detections, which implies related advancement in both of biological structure and detection methods.

Umbilical Cord Blood Betaine in Infants Born Small for Gestational Age.

Background: Birth weight is of importance due to its relation to fetal health, and it's also a predictor of the subsequent development of the child.

Objective: This study aims to assess whether betaine is associated with poor fetal growth.

Design: A case-control study was used in this study.

The association between umbilical cord blood fat-soluble vitamin concentrations and infant birth weight.

Background: Fat-soluble vitamins, including vitamins A, D and E, play an important role in the regulation of glucose and lipid metabolism, and may affect infant birth weight. Evidence on the association of birthweight with fat-soluble vitamins is controversial. Therefore, this study aims is to determine the associations of birthweight with vitamin A, D, and E concentrations in cord blood.

Comparison of mothers' perceptions of hunger cues in 3-month-old infant under different feeding methods.

Background: Mothers' perception of infant hunger cues is a critical content of responsive feeding, which is central to the promotion of early childhood development. However, only a few studies have examined responsive feeding in China, especially lacking the studies on perceptions of infant hunger cues. Consider the cultural differences, the aim of this study was to describe the perceptions of infant hunger cues of Chinese mothers for infants aged 3 months, and explore the relationship between maternal perceptions of infant hunger cues and different feeding methods.

Cord blood 25(OH)D, cord blood total immunoglobulin E levels, and food allergies in infancy: A birth cohort study in Chongqing, China.

Background: Food allergy (FA) in infants has become a common disease worldwide. There are many controversies surrounding the relationships among levels of cord blood 25-hydroxy vitamin D [25(OH)D], total immunoglobulin E (IgE), and FA.

Methods: In this study, we recruited pregnant women in the third trimester undergoing obstetric examination in Chongqing City, Western China.

Serum levels of insulin-like growth factor-1 and insulin-like growth factor binding protein-3 in children with autism spectrum disorder.

Objectives: To study the serum levels of insulin-like growth factor-1 (IGF-1) and insulin-like growth factor binding protein-3 (IGFBP-3) in children with autism spectrum disorder (ASD) and their association with the core symptoms of ASD.

Methods: A total of 150 ASD children aged 2-7 years (ASD group) and 165 healthy children matched for age and sex (control group) who were recruited at the outpatient service of Chongqing Health Center for Women and Children were enrolled as subjects. Autism Behavior Checklist (ABC) and Childhood Autism Rating Scale (CARS) were used to evaluate the core symptoms of the ASD children.

A prospective cohort study of cord blood 25(OH)D3 and food allergies in 6-month-old Chinese infants.

Background: Vitamin D is closely related to childhood allergic diseases, such as food allergies, atopic dermatitis, and asthma. However, it is unclear whether vitamin D status in the cord blood from mothers is related to food allergies in infants.

Objective: We performed a prospective cohort study on the relationship between the cord blood vitamin D [i.

Effects of baby-friendly practices on breastfeeding duration in China: a case-control study.

Background: The Baby-Friendly Hospital Initiative is generally considered an effective way to promote breastfeeding. Although China has the largest number of baby-friendly hospitals in the world, research on baby-friendly practices in China is limited, and the rate of exclusive breastfeeding (EBF) at 6 months, 20.7%, compared to the 2025 global goal of 50% is low.

The Possible Effects of Breastfeeding on Infant Development at 3 Months: A Case-Control Study.

To examine the influence of exclusive breastfeeding on infant development among 3-month-old infants in a Chinese population. Mothers and their 3-month-old infants were recruited from four maternal and child health hospitals from April 2018 to March 2019. Based on the infants' feeding patterns, the mother-infant dyads were divided into two groups: exclusive breastfeeding and formula feeding groups.

Using epidemiological data to identify needs for child-rearing support among Chinese parents: a cross-sectional survey of parents of children aged 6 to 35 months in 15 Chinese cities.

Background: The quality of the family environment-in particular, the kind of parenting children receive in their early years-plays a critical role in influencing children's growth and development. To facilitate the development and delivery of appropriate parenting and family interventions for Chinese parents, this study explores the prevalence of the difficulties that may arise in the course of child-rearing, the associated sociodemographic factors and parents' help-seeking behavior.

Methods: A cross-sectional self-reporting survey was conducted with a sample of 2229 parents of children between 6 and 35 months of age.

[A prospective study of the development of nocturnal sleep patterns in infants].

Objective: To investigate the development of nocturnal sleep pattern in infants.

Methods: Fifty healthy full-term newborns born in Chongqing Maternal and Child Health Care Hospital were chosen for a prospective longitudinal study. A non-invasive sleep monitor, Actiwatch, was used to monitor infants' 12 sleep parameters on the 10th day, 28th day, the first Tuesday at the 2nd, 3rd, 4th, 5th, 6th, 9th and 12th month after birth, each monitoring time lasting 60 hours.

[Longitudinal study on infantile nocturnal sleep-wake pattern developmental trajectory with Actiwatch].

Objective: To understand the infantile nocturnal sleep-wake pattern developmental trajectory with Actiwatch, which would benefit the clinical assessment of infantile sleep.

Method: This study was a longitudinal study conducted between 7 Oct, 2009-30 Oct, 2011 in 10 hospitals of 9 cities of China ( Beijing, Xi'an, Qingdao, Wuhan, Changsha, Chongqing, Huzhou, Xiamen and Liuzhou). Actiwatch was used to track the sleep-wake pattern development trajectory of healthy infants in the first year of life in the home setting.

[Effect of eating behavior intervention on infants in the urban area of Chongqing, China].

Objective: To investigate how to establish good eating behavior and correct bad eating habits in infants by means of the child health care outpatient clinic and to promote the growth and development of infants.

Methods: Infants aged 0-3 months, who were randomly selected from the urban area of Chongqing, were divided into intervention and control groups. The infants in the intervention group received all intervention measures in the study, while those in the control group received conventional health care.

[Prevalence and risk factors of overweight and obesity among infants in Chongqing urban area].

Objective: To investigate the prevalence and risk factors of overweight and obesity among infants in Chongqing urban area, and to provide a basis for early intervention in cases of childhood obesity.

Methods: A total of 2139 infants aged one month were selected by stratified cluster sampling. They underwent growth monitoring and evaluation at 3, 6, 9, 12 and 18 months after birth.

[Prognoses of food allergy in infancy].

Objective: Food allergy as one of social health problems has gained more attention of people. However, few reports on prognosis of food allergy, the relation between infant food allergy and other allergic diseases, and factors affecting prognoses of infant food allergy in China. The present study was designed to investigate the evolution of infancy food allergy and to explore predicting factors of the tolerance to these foods and factors of other allergic diseases to provide a clue for managing children with food allergy reasonably and to improve their prognoses.