Publications by authors named "Nianqi Xiao"
The recent development of nanobiomaterials has shed some light on the field of periodontal tissue regeneration. Laponite (LAP), an artificially synthesized two-dimensional (2D) disk-shaped nanosilicate, has garnered substantial attention in regenerative biomedical applications owing to its distinctive structure, exceptional biocompatibility and bioactivity. This study endeavors to comprehensively evaluate the influence of LAP on periodontal regeneration.
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- - This study examines a new biomaterial made from Laponite (LAP) nanosilicate incorporated into Polycaprolactone (PCL) nanofibrous membranes, aiming to enhance periodontal regeneration in both lab and rat models.
- - The PCL/LAP membranes demonstrated strong biocompatibility and promoted the growth and differentiation of periodontal ligament cells (PDLCs), showing potential for improving tissue repair.
- - Additionally, the membranes positively influenced immune responses by encouraging anti-inflammatory activities and macrophage polarization, leading to effective healing of periodontal and calvarial defects in rats.
Critical oral-maxillofacial bone defects, damaged by trauma and tumors, not only affect the physiological functions and mental health of patients but are also highly challenging to reconstruct. Personalized biomaterials customized by 3D printing technology have the potential to match oral-maxillofacial bone repair and regeneration requirements. Laponite (LAP) nanosilicates have been added to biomaterials to achieve biofunctional modification owing to their excellent biocompatibility and bioactivity.
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