Wavelength extension beyond 3 µm in a Ho/Pr co-doped AlF-based fiber laser.

In this Letter, we report continuous-wave (CW) lasers with wavelengths beyond 3 µm in homemade Ho/Pr co-doped AlF-based glass fibers. The laser cavity was established through the integration of a dichroic mirror (DM, HR@3-3.1 µm) positioned at the pump end and a partial reflectivity (PR) fiber Bragg grating (FBG) situated at the laser emission end.

High-frequency neural activity dysregulation is associated with sleep and psychiatric disorders in BMAL1-deficient animal models.

Sleep disturbance led by BMAL1-deficiency has been recognized both in rodent and non-human primate models. Yet it remained unclear how their diurnal brain oscillations were affected upon BMAL1 ablation and what caused the discrepancy in the quantity of sleep between the two species. Here, we investigated diurnal electroencephalographs of BMAL1-deficient mice and cynomolgus monkeys at young adult age and uncovered a shared defect of dysregulated high-frequency oscillations by Kullback-Leibler divergence analysis.

Efficient 2075-nm laser emission from Ho-doped fluorotellurite glass in a compact all-fiber structure.

In this Letter, we report an Ho-doped fluorotellurite glass all-fiber laser at 2075 nm. The gain fiber is pumped in-band with a 1976-nm fiber laser and connected by fusion splicing. A high-quality fusion splicing point with a loss of < 0.

ISX-9 potentiates CaMKIIδ-mediated BMAL1 activation to enhance circadian amplitude.

Circadian dysregulation associates with numerous diseases including metabolic dysfunction, sleep disorder, depression and aging. Given that declined circadian amplitude is a trait commonly found with compromised health, interventions that design in precluding circadian amplitude from dampening will aid to mitigate complex, circadian-related diseases. Here we identify a neurogenic small molecule ISX-9 that is able to support persistent and higher amplitude of circadian oscillations.

Direct femtosecond laser inscription of Bragg gratings in Ho/Pr co-doped AlF-based glass fibers for a 2.86 µm laser.

In this Letter, we report the fabrication of fiber Bragg gratings (FBGs) in home-made Ho/Pr co-doped single-cladding fluoroaluminate (AlF) glass fibers and its application in watt-level lasing at the mid-infrared (MIR) wavelength of 2.86 µm. The FBGs were inscribed using an 800 nm femtosecond (fs) laser direct-writing technique.

Room-temperature watt-level and tunable ∼3 µm lasers in Ho/Pr co-doped AlF-based glass fiber.

A room-temperature watt-level continuous-wave-output power mid-infrared fiber laser operating at $\lambda\sim 3\; \unicode{x00B5}{\rm m}$ is demonstrated using a ${{\rm Ho}^{3 +}}/{{\rm Pr}^{3 +}}$ co-doped ${{\rm AlF} _3}$ based glass fiber as a gain fiber. This fixed-wavelength laser had maximum output power of 1.13 W with a slope efficiency of 10.

2.9 µm lasing from a Ho/Pr co-doped AlF-based glass fiber pumped by a 1150 nm laser: publisher's note.

This publisher's note contains corrections to Opt. Lett. 45, 1216 (2020).

2.9 µm lasing from a Ho/Pr co-doped AlF-based glass fiber pumped by a 1150 nm laser.

/ co-doped -based glass fibers were fabricated by using a rod-in-tube method based on the matrix glass composition of --------. Under the pump of a 1150 mW Raman fiber laser, a 2.9 µm laser was observed in a 19 cm long / co-doped -based glass fiber with an output power of 173 mW and a slope efficiency of 10.

Luteolin reduces inflammation in Staphylococcus aureus-induced mastitis by inhibiting NF-kB activation and MMPs expression.

Mastitis is a serious and prevalent disease caused by infection by pathogens such as Staphylococcus aureus. We evaluated the anti-inflammatory effects and mechanism of luteolin, a natural flavonoid with a wide range of pharmacological activities, in a mouse model of S. aureus mastitis.

Piperine Plays an Anti-Inflammatory Role in Staphylococcus aureus Endometritis by Inhibiting Activation of NF-κB and MAPK Pathways in Mice.

Endometritis is commonly caused by pathogenic microorganisms, including Staphylococcus aureus (S. aureus). Piperine, which is a natural medicine, has shown a variety of biological activities.

RETRACTED: Sophocarpine displays anti-inflammatory effect via inhibiting TLR4 and TLR4 downstream pathways on LPS-induced mastitis in the mammary gland of mice.

Mastitis is defined as the inflammation of the mammary gland. LPS, which is widely used to induce mastitis models for the study of this disease, triggers similar inflammation as Escherichia coli. Sophocarpine, isolated from Sophora alopecuroides L.