Publications by authors named "Nianfu Song"
Pulmonary Hypertension and Anastrozole (PHANTOM): A Randomized, Double-Blind, Placebo-Controlled Trial.
Am J Respir Crit Care Med
November 2024
Inhibition of aromatase with anastrozole reduces pulmonary hypertension in experimental models. We aimed to determine whether anastrozole improved the 6-minute-walk distance (6MWD) at 6 months in pulmonary arterial hypertension (PAH). We performed a randomized, double-blind, placebo-controlled phase II clinical trial of anastrozole in subjects with PAH at seven centers.
View Article and Find Full Text PDFEffects of Aircraft Noise on Sleep: Federal Aviation Administration National Sleep Study Protocol.
Int J Environ Res Public Health
November 2023
Aircraft noise can disrupt sleep and impair recuperation. The last U.S.
View Article and Find Full Text PDFArticle Synopsis
- Sorafenib did not significantly improve the alveolar-arterial oxygen gradient (AaPO) in patients with hepatopulmonary syndrome (HPS) compared to a placebo after 3 months.
- Despite reducing certain angiogenic markers, such as vascular endothelial growth factor receptors, sorafenib negatively impacted mental quality of life scores, indicating potential adverse effects.
- Future research should explore different antiangiogenic therapies or approaches targeting other disease pathways for better treatment options in HPS.