Publications by authors named "Nianci Shen"
Background And Objectives: To explore whether Rose Bengal-induced photochemical crosslinking (RB-PCL) can be a replacement for sutures in conjunctival autograft bonding, we compared the safety, operating time, postoperative ocular signs, and inflammatory responses of RB-PCL versus nylon suturing for sealing conjunctival autografts in rabbits.
Study Design/materials And Methods: Thirty-six New Zealand White rabbits underwent limbal conjunctival autografting using either sutures or RB-PCL to attach conjunctival autografts to the bare sclera. Animals were randomized to one of two groups (18 per group): the suture group or RB-PCL group.
Background And Purpose: The purpose of this study was to investigate the subacute effects of Rose Bengal (RB) and 532 nm green light-induced photochemical crosslinking (RB-PCL) on rabbit thin corneal stability and safety in vivo.
Materials And Methods: Rabbit thin corneal models with 250 μm thickness were created by photorefractive keratectomy surgery. Photochemical crosslinking with green light (wavelength 532 nm) at an illumination intensity of 0.
Purpose: To compare the efficacy of photochemical-induced tissue cross-linking (PCL), utilizing Rose Bengal (RB) and 532 nm green light irradiation (RB-PCL), with standard sutures for closure of penetrating corneal incision in porcine cadaver eyes.
Methods: A full-thickness penetrating incision, 3 mm in length parallel to the limbus and perpendicular to the corneal surface, was made in the enucleated porcine cornea. Photochemical cross-linking was performed with tropical RB application and irradiation of 532 nm green light (0.
In this study, we explore the effect of photochemical activation induced corneal cross-linking, utilizing Rose Bengal (RB) and 532 nm green light irradiation (RB-PCL), on porcine corneal biomechanical rigidity and the biochemical resistance against collagenase digestion. A protocol with a wavelength of 532 nm and illumination intensity of 0.4W/cm(2) for 250 s to deliver a dose of 100 J/cm(2) was chosen.
View Article and Find Full Text PDFObjective: To study the clinical efficacy and safety of the Esculin and Digitalis glycosides Eye Drops used in the patients of ametropic asthenopia.
Methods: Multicenter clinical trial. Asthenopia patients were chosen from eleven hospitals cross China from July, 2008 to January, 2009.