Publications by authors named "Nian-zu Yu"
Rare intraspinal clear cell meningioma in children: a case report and literature review.
J Int Med Res
October 2020
Meningioma of the spinal canal is very rare. Clear cell meningioma (CCM) with special histological features occurs more commonly in the spinal cord. A review of the published English-language literature identified 40 reported cases of children with intraspinal CCM and this current report presents an additional case of a 3-year-old child with confirmed lumbar CCM.
View Article and Find Full Text PDFAssociation Between Meteorological Factors and the Rupture of Intracranial Aneurysms.
J Am Heart Assoc
September 2019
Background Both meteorological factors and morphological factors are important factors to predict intracranial aneurysm rupture. This study investigated the relationship between meteorological factors and aneurysmal subarachnoid hemorrhage (aSAH). Additionally, the morphological differences between ruptured and unruptured aneurysms under these high-risk meteorological conditions were assessed.
View Article and Find Full Text PDFArticle Synopsis
- The study investigates the role of hemodynamic conditions in the development of intracranial aneurysms (IA) and how they affect endothelial cell (EC) functions.
- A modified T chamber system simulates artery bifurcation, showing that increased flow rates lead to reduced expression of key proteins in normal and P120 catenin (P120ctn) knockdown human umbilical vein ECs, suggesting altered cell adhesion and morphology.
- The research indicates that loss of P120ctn, influenced by hemodynamic changes, could weaken adherens junctions between ECs, potentially leading to inflammation and contributing to the formation of IA.
Background: Understanding the risk factors for the formation of de novo intracranial aneurysms (IAs) is important for patients who have ever suffered a cerebral aneurysm.
Objective: To estimate the risk factors for the development of a de novo IA to identify which patients need more aggressive surveillance after aneurysm treatment.
Methods: We followed the preferred reporting items for systematic reviews and meta-analyses guidelines and searched the PubMed, CENTRAL, EMBASE, and LILACS databases using the key words cerebral aneurysms, de novo, IAs, risk factors combined using and/or.
[The expression and role of Cathepsin B in intracranial aneurysm wall].
Zhonghua Wai Ke Za Zhi
March 2010
Objectives: To detect the expression of Cathepsin B (CatB) in the intracranial aneurysm wall and its effect to the apoptosis of vascular smooth muscle cells, aimed at clarifying the pathological formation mechanism of intracranial aneurysm.
Methods: From November 2006 to February 2009, 20 intracranial aneurysm samples were collected as the experimental group, and 6 cases of normal pallium artery samples were collected as the control group. Immunohistochemical technique was used to evaluate the expressions of CatB, alpha-smooth muscle actin (alpha-SMA) and Caspase-3.