Cold snaps lead to a 5-fold increase or a 3-fold decrease in disease proliferation depending on the baseline temperature.

Background: Climate change is driving increased extreme weather events that can impact ecology by moderating host-pathogen interactions. To date, few studies have explored how cold snaps affect disease prevalence and proliferation. Using the Daphnia magna-Ordospora colligata host-parasite system, a popular model system for environmentally transmitted diseases, the amplitude and duration of cold snaps were manipulated at four baseline temperatures, 10 days post-exposure, with O.