Key Points: The 2015 Kidney Disease Outcomes Quality Initiative Guideline Update increased the contribution of residual kidney function, shortening the time required for twice weekly hemodialysis. No study had yet assessed the feasibility of prescribing twice weekly hemodialysis according to the updated guideline. Twice weekly hemodialysis prescribed using the updated guideline maintained quality of life and controlled fluid gain, potassium, and uremic solutes.
View Article and Find Full Text PDFPruritus is a common debilitating symptom experienced by hemodialysis patients. Treatment is difficult because the cause of uremic pruritus is not known. This study addressed the hypothesis that pruritus is caused by solutes that accumulate in the plasma when the kidneys fail.
View Article and Find Full Text PDFClin J Am Soc Nephrol
January 2008
Background And Objectives: Protein-bound solutes are poorly cleared by peritoneal dialysis. We examined the hypothesis that plasma concentrations of bound solutes would therefore rise as residual renal function is lost.
Design, Setting, Participants, & Measurements: Clearances of urea indican and p-cresol sulfate were measured in peritoneal dialysis patients with and without residual function.