Publications by authors named "Nham Thi Phuong Linh"
Article Synopsis
- Ovarian cancer is highlighted as a serious and common type of cancer with a high death rate.
- A new ovarian high-grade serous cancer cell line, named M4, was isolated from a Vietnamese patient's tumor and showed strong growth and stability in lab culture.
- The M4 cells exhibited key characteristics of cancer cells, including distinct shapes, large nuclei, and the presence of specific cancer markers like CA125, p53, and Ki67.
The safety of CAR-T cells and PD-1 antibody combination on an experimental model.
Biochem Biophys Res Commun
March 2023
Chimeric antigen receptor (CAR) T cells and PD-1 antibodies (PD-1 Ab) are emergent immunotherapies with unprecedented efficacy. The presence of PD-1 on T cells contributes to hypofunction of CAR-T therapy and inhibition of PD-1 enhances anti-cancer effect of CAR-T cells. Therefore, the combination of CAR-T cells and PD-1 antibody is a promissing strategy for cancer treatment.
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