Management of anterior and posterior crossbites with lingual appliances and miniscrew-assisted rapid palatal expansion: A case report.

Rationale: Current literature describes only 2 cases combining miniscrew-assisted rapid palatal expansion (MARPE) with lingual appliances. These cases require 2 impressions, 1 before and 1 after palatal expansion, to ensure accurate lingual appliance placement, potentially increasing treatment time and cost. This case report aimed to demonstrate a modified workflow of combining MARPE and lingual appliances in managing an adult patient with anteroposterior and transversal discrepancies, requiring only a single digital impression for both fabrication and positioning.

Management of a severe skeletal Class II hyperdivergent patient with asymmetric missing teeth with lingual appliances and mandibular osteotomy: A case report.

Rationale: Orthognathic surgery cases are inherently challenging to treat with lingual appliances due to the complexities of orthodontic management and difficulties in achieving intermaxillary fixation during surgery. This challenge is further amplified in cases involving asymmetric space closure, such as those with a missing molar on one side and a premolar on the other, a scenario not yet documented in the literature. This case report presents the orthodontic-orthognathic management of an adult patient requiring space closure of asymmetric missing lower teeth.

Micrometer-Resolution Fluorescence and Lifetime Mappings of CsPbBr Nanocrystal Films Coupled with a TiO Grating.

Enhancing light emission from perovskite nanocrystal (NC) films is essential in light-emitting devices, as their conventional stacks often restrict the escape of emitted light. This work addresses this challenge by employing a TiO grating to enhance light extraction and shape the emission of CsPbBr nanocrystal films. Angle-resolved photoluminescence (PL) demonstrated a 10-fold increase in emission intensity by coupling the Bloch resonances of the grating with the spontaneous emission of the perovskite NCs.

Restoration of Anterior Teeth Defect With Porcelain Laminate Veneer Using the Refractory Technique: A Case Report.

Anterior teeth play an important role in the aesthetic appearance of an individual. Hence, restoration of the anterior teeth has always been a significant concern for both dentists and patients worldwide. Indirect restoration using laminate veneers has revolutionized cosmetic dentistry by minimizing tooth preparation compared to full dental crowns.

Orthodontic Retreatment of an Adult Bimaxillary Protrusion Patient With Lingual Appliances and Premolar Extractions: A Case Report.

Orthodontic relapse and the demand for improved esthetics often necessitate retreatment in adult patients. This case report highlights the successful management of an adult female patient with bimaxillary protrusion, previously treated with a non-extraction approach. Treatment included lingual passive self-ligating appliances, premolar extractions, and mini-screws to reinforce anchorage.

Correction of a severe post-surgical iatrogenic class II anterior open bite with lingual appliances and mini-screws: a case report.

An iatrogenic open bite after orthognathic surgery is an uncommon malocclusion, with only one documented case reported in the literature. However, the open bite in this case report was not a true open bite, as it resulted from the interferences between the maxillary second molars and mandibular retromolar bones. This case report aims to present the management of a true iatrogenic open bite with posterior teeth in centric occlusion, occurring after mandibular setback surgery.

Comparison of the Marginal and Internal Fit of Ceramic Laminate Veneers Fabricated with Four Different Computer-Aided Manufacturing Techniques.

Purpose: The improvement of computer-aided design and computer-aided manufacturing (CAD/CAM) has changed the methods of fabricating laminate veneers. The objectives of this study were to evaluate the marginal and internal fit of ceramic veneers manufactured with different CAD/CAM techniques. Materials and methods: A metal die was made by copying a prepared plastic maxillary central right incisor and scanned for designing a laminate veneer.

In silico screening of Fyn kinase inhibitors using classification-based QSAR model, molecular docking, molecular dynamics and ADME study.

This study aimed to use a computational approach that combined the classification-based QSAR model, molecular docking, ADME studies, and molecular dynamics (MD) to identify potential inhibitors of Fyn kinase. First, a robust classification model was developed from a dataset of 1,078 compounds with known Fyn kinase inhibitory activity, using the XGBoost algorithm. After that, molecular docking was performed between potential compounds identified from the QSAR model and Fyn kinase to assess their binding strengths and key interactions, followed by MD simulations.

3D-printed indirect bonding trays and transfer jigs for lingual brackets: Digital workflows and two case reports.

With the advancement of 3-dimensionally (3D) printing technology, orthodontists can design and fabricate 3D-printed indirect bonding trays and transfer jigs for lingual brackets independently from the laboratory. The present article describes, in detail, the digital workflows for designing and fabricating 3D-printed lingual bracket indirect bonding trays and transfer jigs. Additionally, it aims to demonstrate the effectiveness of this approach in managing common orthodontic issues in adult patients.

Lingual bracket transfer accuracy of double vacuum-formed indirect bonding tray using 3D-printed model: an in vivo study.

Introduction: This study aimed to assess the transfer accuracy of a digital indirect bonding method for lingual brackets using double vacuum-formed trays in vivo.

Methods: Twenty-five patients in need of lingual orthodontic treatment were consecutively recruited. Bracket placement was performed on ideal setups, followed by fabricating indirect bonding trays through vacuum-forming on 3-dimensional printed models.

Urban Sanitation: New Terminology for Globally Relevant Solutions?

Progress toward Sustainable Development Goals for global access to safe sanitation is lagging significantly. In this Feature, we propose that misleading terminology leads to errors of categorization and hinders progress toward sanitation service provision in urban areas. Binary classifications such as "offsite/onsite" and "sewered/nonsewered" do not capture the need for "transport to treatment" or the complexity of urban sanitation and should be discarded.

An effective and comprehensible method to detect and evaluate retinal damage due to diabetes complications.

The leading cause of vision loss globally is diabetic retinopathy. Researchers are making great efforts to automatically detect and diagnose correctly diabetic retinopathy. Diabetic retinopathy includes five stages: no diabetic retinopathy, mild diabetic retinopathy, moderate diabetic retinopathy, severe diabetic retinopathy and proliferative diabetic retinopathy.

Modelling the spread and mitigation of an emerging vector-borne pathogen: Citrus greening in the U.S.

Predictive models, based upon epidemiological principles and fitted to surveillance data, play an increasingly important role in shaping regulatory and operational policies for emerging outbreaks. Data for parameterising these strategically important models are often scarce when rapid actions are required to change the course of an epidemic invading a new region. We introduce and test a flexible epidemiological framework for landscape-scale disease management of an emerging vector-borne pathogen for use with endemic and invading vector populations.

Evaluation of water safety plan implementation at provincial water utilities in Vietnam.

This study evaluated the experience of implementing water safety plans (WSPs) in Vietnam. WSPs were introduced in Vietnam by the World Health Organization (WHO) in collaboration with the Ministry of Construction in 2006 and have been a mandatory requirement for municipal water supplies since 2012. Using a mixed-methods approach, we collected data on the perceived benefits and challenges of WSP implementation from 23 provincial water companies between August and November 2021.

Preclinical Immune Response and Safety Evaluation of the Protein Subunit Vaccine Nanocovax for COVID-19.

The coronavirus disease 2019 (COVID-19) pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a global health concern. The development of vaccines with high immunogenicity and safety is crucial for controlling the global COVID-19 pandemic and preventing further illness and fatalities. Here, we report the development of a SARS-CoV-2 vaccine candidate, Nanocovax, based on recombinant protein production of the extracellular (soluble) portion of the spike (S) protein of SARS-CoV-2.

An Initial 5-Year Single-Center Experience of 365 Patients Undergoing the Video-Assisted Thoracoscopic Surgery for Nuss Procedure for Pectus Excavatum in Resource-Scare Setting.

Little is known about video-assisted thoracoscopic surgery in the Nuss procedure (VATS-NUSS) and its postoperative outcomes in the resource-scarce conditions in clinical practice such as Vietnam. Available evidence in the literature was mostly reported from large institutions in developed countries. Hence, this study was conducted to review our initial large single-center experience in the use of the VATS-NUSS for patients with pectus excavatum (PE) within 5 years.

Skeletal Class III Malocclusion with Lateral Open Bite and Facial Asymmetry Treated with Asymmetric Lower Molar Extraction and Lingual Appliance: A Case Report.

A skeletal Class III malocclusion with open bite tendency is considered very difficult to treat orthodontically without surgery. This case report describes the lingual orthodontic treatment of an adult skeletal Class III patient with mandibular deviation to the left side, lateral open bite, unilateral posterior crossbite, zero overbite and negative overjet. The lower incisors were already retroclined to compensate with the skeletal discrepancy.

Management of an adult patient with missing one mandibular incisor, severe overjet, and midline discrepancy with asymmetric extraction, lingual appliance, and skeletal anchorage: A case report.

This case report describes the lingual orthodontic treatment of an adult patient with Angle Class I malocclusion, agenesis of mandibular right central incisor, severe overjet and deep overbite, excessive proclination of maxillary and mandibular incisors, and midline discrepancy. Because of unique presentation, symmetric extraction could not be performed in the lower arch of this 34-year-old patient. She was treated with three premolar extractions and absolute anchorage with temporary anchorage devices for maximum retraction of upper anterior teeth.

Structural basis for loading and inhibition of a bacterial T6SS phospholipase effector by the VgrG spike.

The bacterial type VI secretion system (T6SS) is a macromolecular machine that injects effectors into prokaryotic and eukaryotic cells. The mode of action of the T6SS is similar to contractile phages: the contraction of a sheath structure pushes a tube topped by a spike into target cells. Effectors are loaded onto the spike or confined into the tube.

Correction of Upper Incisor Proclination by Applying Lingual Crown Torque with Pre adjusted Lingual Brackets in a Skeletal-Class III Patient - Case Report.

Background: After levelling and alignment in skeletal Class III patients with upper anterior crowding, the upper incisors usually have excessive proclination. In these cases, the upper incisors' axial proclination need to be reduced to improve esthetics.

Case Report: This case report presents an invisible orthodontic treatment of a 24-year-old adult female patient with skeletal Class III relationship, anterior crossbite, proclined upper incisors, and reduced incisor showing.

Modelling quantities and qualities (Q&Q) of faecal sludge in Hanoi, Vietnam and Kampala, Uganda for improved management solutions.

The importance of faecal sludge management is gaining recognition. However, methods are still lacking to reasonably estimate the quantities and qualities (Q&Q) that need to be managed, which makes the planning for and implementing of management solutions quite difficult. The objective of this study was to collect and analyse Q&Q of faecal sludge at a citywide scale, and to evaluate whether "SPA-DET" data (=> spatially analysable - demographic, environmental and technical) could then be used as predictors of Q&Q of faecal sludge.