Publications by authors named "Nguyen Thi Sim"
Article Synopsis
- * Diagnostic challenges arise with oligohydramnios/anhydramnios during pregnancy, but amnioinfusion offers a technique to collect amniotic fluid for genetic testing in cases of suspected urinary tract anomalies.
- * This study reports the first prenatal diagnosis of ARRTD in Vietnam, identifying specific ACE gene variants in fetuses with severe amniotic fluid deficits, which aids in better understanding and counseling for affected families.
Background: Twin reversed arterial perfusion (TRAP) sequence is an extremely rare congenital anomaly in monochorionic (MC) twins. The condition is characterized by a malformed fetus (acardiac twin) without cardiac activities being perfused by a structurally normal one (pump twin) an artery-to-artery anastomosis in a reverse direction.
Case Summary: We described the first case of TRAP to receive laser surgery in Vietnam.
Objective: To evaluate the surgery outcomes of fetoscopic laser ablation (FLA) for selective umbilical cord in treating twin-twin transfusion syndrome (TTTS) with special conditions and neonatal outcomes post-operation.
Methods: A prospective study, 21 monochorionic diamniotic (MCDA) twins diagnosed with TTTS stage II-IV according to Quintero classification from 16 to 26 weeks of gestation, among that, 12 cases of TTTS stage II with selective intrauterine growth restriction (sIUGR), 6 cases of TTTS stage II with proximate cord insertions, 3 cases of TTTS stage IV underwent fetoscopic laser ablation for the selective fetal reduction at Hanoi Obstetrics and Gynecology Hospital from September 2019 to July 2021. Complications and surgical outcomes were noted.
Twin-twin transfusion syndrome (TTTS) is an unusual and serious condition that occurs in twin pregnancies when identical twins share a placenta but develop discordant amniotic fluid volumes. TTTS is associated with an increased risk of fetal death and birth defects if untreated. This study investigated the soluble levels of biomarkers including growth factors and interleukins in pregnant women with and without TTTS during pregnancy.
View Article and Find Full Text PDFBackground: Aneuploidy is a major cause of miscarriages and implantation failure. Preimplantation genetic testing for aneuploidy (PGT-A) by Next Generation Sequencing (NGS) is able to detect of the numeral and structural chromosomal abnormalities of embryos in vitro fertilization (IVF).
Aim: This study was aimed to assess the relationship between maternal age and chromosomal abnormalities NGS technology.