Trop Med Int Health
December 2024
Int J Biol Macromol
December 2024
Polydeoxyribonucleotide (PDRN) is a registered DNA-derived proprietary drug containing a mixture of DNA fragments of molecular weights of 50 and 1500 kDa extracted mainly from salmon with a highly pure active substance (>95 %). It has many valuable medicinal effects and multi-functions related to cosmeceuticals. In-vivo tests and even clinical trials have confirmed this substance as non-toxic.
View Article and Find Full Text PDFAnimal personalities are characterized by intra-individual consistency and consistent inter-individual variability in behaviour across time and contexts. Personalities abound in animals, ranging from sea anemones to insects, arachnids, birds, fish and primates, yet the pathways mediating personality formation and expression remain elusive. Social conditions during the early postnatal period are known determinants of mean behavioural trait expressions later in life, but their relevance in shaping personality trajectories is unknown.
View Article and Find Full Text PDFPhytochemical investigation of the methanol extract of the aerial parts of Lysimachia laxa led to the isolation of four new oleanane-type saponins, lysimosides A-D (1-4) and one known compound, lysimachigenoside B (5). Their structures were elucidated using a combination of HR-ESI-MS, 1D and 2D-NMR spectral data, chemical methods, and comparison with previous literature. The cytotoxic activity of these compounds was evaluated against human lung cancer (A-549) and human breast cancer (MCF-7) cell lines.
View Article and Find Full Text PDFBiochem Biophys Res Commun
July 2024
In this study, a simple green synthesis of vanadium pentoxide nanoparticles (VNPs) was prepared by the extract of Kaffir lime fruit (Citrus hystrix) as a green reducing and stabilizing agent, along with the investigation of calcination temperature was carried out at 450 and 550 °C. It was affirmed that, at higher temperature (550 °C), the VNPs possessed a high degree crystalline following the construction of (001) lattice diffraction within an increase in crystalline size from 47.12 to 53.
View Article and Find Full Text PDFAnimal personalities are defined by within-individual consistency, and consistent among-individual variation, in behavior across time and/or contexts. Here we hypothesized that brief early-life experience of intraguild predation (IGP) risk has enduring phenotypic effects on personality expression in boldness and aggressiveness in later life. We tested our hypothesis in predatory mites , which are IG predators with ontogenetic role reversals, i.
View Article and Find Full Text PDFNine pentacyclic triterpene derivatives including new 3-coumaroyl trichadenic acid B () and two new ursane-type triterpene derivatives, 11,12-[1-(methyl)-2-(4-hydroxy-3-methoxyphenyl)ethane-1,2-dioxy]-urs-12-ene-3-ol () and 11,12-[2-(methyl)-1-(4-hydroxy-3-methoxyphenyl)ethane-1,2-dioxy]-urs-12-ene-3-ol () were isolated from the leaves of Ninh., along with six known compounds (). This is the first report on pentacyclic triterpenoids from this species.
View Article and Find Full Text PDFMicrobial communities in mangrove forests have recently been intensively investigated to explain the ecosystem function of mangroves. In this study, the soil microbial communities under young (<11 years-old) and old (>17 years-old) mangroves have been studied during dry and wet seasons. In addition, biogeochemical properties of sediments and methane emission from the two different mangrove ages were measured.
View Article and Find Full Text PDFIntense mate competition favors the evolution of extraordinary mating strategies such as the ability of males to identify premature females that are close to becoming mature and associate with them until they are sexually receptive (dubbed precopulatory mate guarding). Owing to possible take-overs by rival males, precopulatory guarding is a high-risk, time- and energy-intensive strategy. Here, we provide experimental evidence that guarding spider mite males undress females by actively removing the exuvia during ecdysis to adult; females undressed by guarding males eclose faster than unguarded females.
View Article and Find Full Text PDFPharmaceuticals (Basel)
April 2023
Alzheimer's disease (AD) is the most common form of dementia. It increases the risk of other serious diseases and causes a huge impact on individuals, families, and socioeconomics. AD is a complex multifactorial disease, and current pharmacological therapies are largely based on the inhibition of enzymes involved in the pathogenesis of AD.
View Article and Find Full Text PDFA series of 1H-1,2,3-triazole-4H-chromene-D-glucose hybrid compounds 7a-w were synthesized using click chemistry of 2-amino-7-propargyloxy-4H-chromene-3-carbonitriles 5a-w. CuNPs@montmorillonite was used as a catalyst in the presence of DIPEA as an additive for this chemistry. All synthesized 1H-1,2,3-triazoles were examined for in vitro inhibition against Mycobacterium tuberculosis protein tyrosine phosphatase B (MtbPtpB).
View Article and Find Full Text PDFIn this study, the click chemistry between N-propargyl derivatives of substituted 4H-pyrano[2,3-d]pyrimidines and tetra-O-acetyl-α-d-glucopyranosyl azide carried out under catalytic conditions using catalyst CuI@Montmorillonite and additive N,N-diisopropylethylamine (DIPEA). The yields of obtained hybrid compounds having 4H-pyrano[2,3-d]pyrimidine connected to 1H-1,2,3-triazole rings were about 85-94 %. All these synthesized hybrid compounds were examined for in vitro α-amylase (with IC values in the range of 103.
View Article and Find Full Text PDFThis study attempted to use fishery processing wastes to produce protease by TKU051. Of the tested wastes, tuna head powder (THP) was found to be the most effective carbon and nitrogen (C/N) source, and the optimal conditions were as follows: 0.811% THP, 0.
View Article and Find Full Text PDFα-Amylase inhibitors (aAIs) have been applied for the efficient management of type 2 diabetes. The aim of this study was to search for potential aAIs produced by microbial fermentation. Among various bacterial strains, TUN03 was found to be a potential aAI-producing strain, and shrimp heads powder (SHP) was screened as the most suitable C/N source for fermentation.
View Article and Find Full Text PDFChemoresistive gas sensors play an important role in detecting toxic gases for air pollution monitoring. However, the demand for suitable nanostructures that could process high sensing performance remains high. In this study, hollow ZnO nanorices were synthesized by a simple hydrothermal method to detect NO and SO toxic gases efficiently.
View Article and Find Full Text PDFThe use of copper nanoparticles for the inhibition of plant pathogens , which causes wilt disease, and , which causes citrus canker, was investigated in this study. To avoid the inhibiting effect of Cu ions on the bacterial cells, the copper nanoparticles were synthesized in the cathode chamber of a non-external circuit bioelectrochemical system (nec_BES) inoculated with sp. HN-41 at the anode.
View Article and Find Full Text PDFRecently, microbial prodigiosin (PG) has received much attention due to its numerous beneficial applications. The aim of this study was to establish the bioprocessing of marine chitinous wastes (MCWs) for the cost-effective preparation of PG. Of the MCWs, demineralized shrimp shell powders (de-SSP) were found to be a potential source of carbon/nitrogen (C/N) for PG production by bacterial fermentation using strains.
View Article and Find Full Text PDFThe effectiveness of peroxymonocarbonate (HCO ) on the degradation of Reactive Blue 19 (RB19) textile dye was investigated in this study. The formation kinetics of HCO produced in a HO - HCO system was studied to control the experimental conditions for the investigation of RB19 degradation at mild conditions. The effects of metallic ion catalysts, the pH, the input HCO and Co concentrations, and UV irradiation were studied.
View Article and Find Full Text PDFWe sampled nasal-pharyngeal throat swabs from 96,123 asymptomatic individuals at risk of SARS-CoV-2 infection, and generated 22,290 pools at collection, each containing samples from two to seven individuals. We detected SARS-CoV-2 in 24 pools, and confirmed the infection in 32 individuals after resampling and testing of 104 samples from positive pools. We completed the testing within 14 days.
View Article and Find Full Text PDFBackground: Multidrug resistant tuberculosis (MDR-TB) remains a serious public health problem with poor treatment outcomes. Predictors of poor outcomes vary in different regions. Vietnam is among the top 30 high burden of MDR-TB countries.
View Article and Find Full Text PDFIn this study, different pretreatment strategies of sugarcane bagasse prior to citric acid modification were investigated in terms of Pb adsorption capacity. Pretreatment strategies included the use of NaOH, HCl, and CHOH in various concentrations. In order to fundamentally understand how these pretreatment methods affect the modification of sugarcane bagasse by citric acid as well as the Pb adsorption capacity of sugarcane bagasse, three main components of sugarcane bagasse namely cellulose, hemicellulose, and lignin were isolated and esterified by citric acid under the same conditions.
View Article and Find Full Text PDFMarine chitins (MC) have been utilized for the production of vast array of bioactive products, including chitooligomers, chitinase, chitosanase, antioxidants, anti-NO, and antidiabetic compounds. The aim of this study is the bioprocessing of MC into a potent anticancer compound, prodigiosin (PG), via microbial fermentation. This bioactive compound was produced by TKU011 with the highest yield of 4.
View Article and Find Full Text PDFIn this study, we firstly aimed to use Nb as dopant to dope into the TiO lattice in order to narrow band gap energy or enhance photocatalytic activity of the Nb-TiO. Then, the prepared Nb-TiO was combined with g-CN to establish Nb-TiO/g-CN direct Z-scheme system for superior reduction of CO into valuable fuels even under visible light. The obtained results indicated that the band gap energy of the Nb-TiO (2.
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