Alkaloids from with inhibitory effect on nitric oxide production lipopolysaccharide-stimulated in RAW264.7 macrophages.

The chemical study of the acidic extract of leaves led to the isolation of one new alkaloid, vietnamine A () and eight known alkaloids (,)-2N-norberbamunine (), grisabine (), -dimethylgrisabine (), dauricine (), neothalibrine (), vietnamine (), xylopine (), and argentinine () by NMR and MS and comparing with the data reported in the literature. Compounds - were evaluated for inhibitory NO production in RAW 264.7 macrophages, LPS-stimulated.

An investigation of antitumor efficiency of novel sustained and targeted 5-fluorouracil nanoparticles.

Traditional chemotherapeutic drugs remain the major treatment for advanced colorectal cancer. However, due to the lack of tumor specificity these drug also destroy healthy tissue and organs, which has been the main reason for treatment failure and mortality. Folate-based drug delivery systems for improving nanoparticle endocytosis have been used to address these problems.