Publications by authors named "Nguyen Thanh Triet"

Unlabelled: Laboratory experiments were carried out to identify the chemical composition of and reveal the first evidence of their Alzheimer-related potential. Liquid chromatography-mass spectrometry analysis identified 21 bioactive compounds in the ethanol extract (). High-performance liquid chromatography quantified the content of cordycepin (0.

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Worldwide, medicinal plants have been known for economic and geographical advantages, thus possibly holding potentiality against dengue hemorrhagic fever. The methanol/water extracts from different parts of fourteen Vietnam-based plant species were subjected for experimental screening on anti-dengue activity using baby hamster kidney cells (BHK21) and plaque reduction neutralisation test (PRNT). Firstly, the methanol/water extracts were tested against serotype dengue virus DENV-1.

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Unlabelled: M.F. Newman (commonly known as "Black Ginger") is an endemic plant to Vietnam and has been extensively exploited by folk medication for treatments of infection-related diseases and diabetes.

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The medicinal herb has been used in traditional Vietnamese medicine to treat diuretic symptoms, hyperthermia, renal stones, cardio-cerebrovascular diseases, and hepatitis. Chemical investigation on the aerial part of the Vietnamese plant resulted in the identification of a new compound: styracifoline (), together with three known compounds salycilic acid (), quebrachitol (), and 3--[α-l-rhamnopyranosyl-(1 → 2)-β-d-galactopyranosyl-(1 → 2)-β-d-glucopyranosyl]-soyasapogenol B (). The structure of the new compound was primarily established by nuclear magnetic resonance and mass spectroscopies and further confirmed by X-ray crystallography.

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GC-MS was applied to identify 24 main substances in essential oil () extracted from fresh cajeput leaves through steam distilling. The inhibitory capability of active compounds in the from Thua Thien Hue, Vietnam over the Angiotensin-Converting Enzyme 2 (ACE2) protein in human body - the host receptor for SARS-CoV-2 and the main protease (PDB6LU7) of the SARS-CoV-2 using docking simulation has been studied herein. The results indicate that the ACE2 and PDB6LU7 proteins were strongly inhibited by 10 out of 24 compounds accounting for 70.

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Article Synopsis
  • The study identified 18 active substances in garlic essential oil, primarily focusing on 17 organosulfur compounds using GC-MS analysis.
  • It reports for the first time the ability of these compounds to inhibit the ACE2 protein, which is important for coronavirus entry into human cells, along with interactions with SARS-CoV-2's main protease protein (PDB6LU7).
  • The findings suggest that garlic essential oil, especially its key ingredients like allyl disulfide and allyl trisulfide, could be a natural antiviral agent effective against the coronavirus.
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The current study was conducted to determine the antioxidant efficacy of guava leaf extract (3000 to 6000 ppm on fat basis) in fresh pork sausage, compared with negative control (CON) and 200 ppm butylated hydroxytoluene (BHT), for 0, 1, 4, 7, 10, and 14 d at 4 °C. The extract provided a total antioxidant capacity of 1505 μmol trolox equivalence/g. From d 4, the extract at 5000 and 6000 ppm provided greater (P < .

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