Scope: Kaempferol (KMP), a bioactive flavonoid compound found in fruits and vegetables, contributes to human health in many ways but little is known about its relationship with muscle mass. The effect of KMP on C2C12 myoblast differentiation and the mechanisms that might underlie that effect are studied.
Methods And Results: This study finds that KMP (1, 10 µM) increases the migration and differentiation of C2C12 myoblasts in vitro.