Publications by authors named "Nguyen T Son"

Background: Vulvovaginal candidiasis and urinary tract infections caused by are common diseases. While the most common causative agent is , other species, such as non-, can also be responsible. Susceptibility to antifungal drugs varies among species, but there is very limited information available from Vietnam.

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  • The study focused on evaluating the antimicrobial resistance patterns in MRSA strains obtained from patients at Bac Ninh Provincial General Hospital in Vietnam, highlighting serious public health concerns.
  • Out of 15,232 clinical samples, 2.7% showed MRSA presence, with the majority coming from wound infections and surgical units.
  • The findings revealed high resistance rates, particularly to azithromycin, while MRSA strains remained fully susceptible to vancomycin, indicating an urgent need for better antibiotic management strategies.
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Background: Excess fibrotic remodeling causes cardiac dysfunction in ischemic heart disease, driven by MAP (mitogen-activated protein) kinase-dependent TGF-ß1 (transforming growth factor-ß1) activation by coagulation signaling of myeloid cells. How coagulation-inflammatory circuits can be specifically targeted to achieve beneficial macrophage reprogramming after myocardial infarction (MI) is not completely understood.

Methods: Mice with permanent ligation of the left anterior descending artery were used to model nonreperfused MI and analyzed by single-cell RNA sequencing, protein expression changes, confocal microscopy, and longitudinal monitoring of recovery.

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Phytochemical investigation of the methanol extract of the aerial parts of Lysimachia laxa led to the isolation of four new oleanane-type saponins, lysimosides A-D (1-4) and one known compound, lysimachigenoside B (5). Their structures were elucidated using a combination of HR-ESI-MS, 1D and 2D-NMR spectral data, chemical methods, and comparison with previous literature. The cytotoxic activity of these compounds was evaluated against human lung cancer (A-549) and human breast cancer (MCF-7) cell lines.

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This study conducted biostatistical multivariate analyses on 23 craniodental morphological measurements from 209 specimens to study interspecific variations amongst 15 bat species of the genus in Vietnam. Univariate and multivariate analyses demonstrated that the studied species can be divided into four groups as follows: extra-large-sized species (), large-sized species (, and ), medium-sized species (, , , , , and ) and small-sized species (, M.aff.

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CuCoFe-LDO/BCD was successfully synthesized from CuCoFe-LDH and biochar derived from durian shell (BCD). Ciprofloxacin (CFX) degraded more than 95% mainly by O and O in CuCoFe-LDO/BCD(2/1)/PMS system within 10 min with a rate constant of 0.255 min, which was 14.

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Quantum state readout is a key requirement for a successful qubit platform. In this work, we demonstrate a high-fidelity quantum state readout of a V2 center nuclear spin based on a repetitive readout technique. We demonstrate up to 99.

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Molecular and dissociative hydrogen adsorption of transition metal (TM)-doped [MoS] atomic clusters were investigated using density functional theory calculations. The introduced TM dopants form stable bonds with S atoms, preserving the geometric structure. The S-TM-S bridging bond emerges as the most stable configuration.

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  • A method was developed to create cobalt ferrite/graphene quantum dot nanoparticles (CF/GQDs) through a thermal hydrolysis process using iron nitrate, cobalt nitrate, and starch at temperatures of 140, 180, and 200 °C for 24 hours.
  • The resulting CF/GQDs nanoparticles, characterized using various techniques, showed sizes of around 8-10 nm and exhibited promising fluorescent and superparamagnetic properties essential for catalytic use.
  • These nanoparticles effectively catalyze the degradation of methylene blue dye under visible light and can be recycled using a magnetic field, maintaining about 95% efficiency even after three uses.
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In this study, two undescribed compounds (1 and 2), together with eight known compounds (3-10) were isolated from the aerial parts of Piper samentosum by various chromatography methods. Their chemical structures were determined to be 7'''-oxolyciumamide N (1), vitexin 2''-O-β-D-(6'''-feruloyl)-glucopyranoside (2), 1,2-dihydro-6,8-dimethoxy-7-hydroxy-1-(3,4-dihydroxyphenyl)-N,N-bis-[2-(-hydroxyphenyl)ethyl]-2,3-napthalene dicarboamide (3), vitexin 6''-O-β-D-glucopyranoside (4), vitexin 2''-O-α-L-rhamnopyranoside (5), methyl 2-hydroxybenzoate-2-O-β-D-apiofuranosyl-(1→2)-O-β-D-glucopyranoside (6), ficuside G (7), methyl 2-O-β-D-glucopyranosylbenzoate (8), methyl 2,5-dihydroxybenzoate-5-O-β-D-glucopyranoside (9), and 3,7-dimethyloct-1-ene-3,6,7-triol 6-O-β-D-glucopyranoside (10) by spectroscopic data analysis including HR-ESI-MS, 1D-, and 2D-NMR spectra. Compounds 1-5 inhibited nitric oxide production in LPS-stimulated RAW264.

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Nuclear spins with hyperfine coupling to single electron spins are highly valuable quantum bits. Here we probe and characterize the particularly rich nuclear-spin environment around single silicon vacancy color centers (V2) in 4H-SiC. By using the electron spin-3/2 qudit as a four level sensor, we identify several sets of ^{29}Si and ^{13}C nuclear spins through their hyperfine interaction.

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  • This study focuses on Burkholderia dolosa, a dangerous pathogen that can cause infections in hospitalized patients, especially those with strokes. A specific isolate, B. dolosa N149, was characterized as highly resistant to many antibiotics and exceptionally virulent.
  • Using advanced genetic techniques, the researchers identified that this strain had resistance to 31 antibiotics and showcased various mechanisms like multidrug efflux pumps that contribute to its drug resistance.
  • The genome analysis revealed numerous virulence genes linked to its ability to cause disease, and B. dolosa N149 was classified as a new sequence type, furthering understanding of its genetic diversity and potential threat in clinical settings.
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  • Probiotics, like LabMix, are beneficial bacteria that help improve gut health by balancing intestinal flora and inhibiting harmful microbes.
  • In safety tests on mice and rats, LabMix showed no toxic effects or significant changes in blood parameters, and it was well-tolerated without impacting normal growth.
  • The study suggests LabMix may be safe for humans and beneficial in reducing inflammation, but more research is needed before it can be mass-produced and sold.
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Purpose: is a commensal bacteria species that can cause various illnesses, from mild skin infections to severe diseases, such as bacteremia. The distribution and antimicrobial resistance (AMR) pattern of varies by population, time, geographic location, and hospital wards. In this study, we elucidated the epidemiology and AMR patterns of isolated from a general hospital in Vietnam.

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Antiphospholipid antibodies (aPL) in primary or secondary antiphospholipid syndrome (APS) are a major cause for acquired thrombophilia, but specific interventions preventing autoimmune aPL development are an unmet clinical need. Although autoimmune aPL cross react with various coagulation regulatory proteins, lipid-reactive aPL, including those derived from patients with COVID-19, recognize the endolysosomal phospholipid lysobisphosphatidic acid presented by the cell surface-expressed endothelial protein C receptor. This specific recognition leads to complement-mediated activation of tissue factor (TF)-dependent proinflammatory signaling and thrombosis.

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Spin-active quantum emitters have emerged as a leading platform for quantum technologies. However, one of their major limitations is the large spread in optical emission frequencies, which typically extends over tens of GHz. Here, we investigate single V vanadium centres in 4H-SiC, which feature telecom-wavelength emission and a coherent S = 1/2 spin state.

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  • Protease activated receptors (PARs) link blood clotting processes with immune responses, and PAR2 signaling, particularly involving tissue factor (TF) and factor VIIa (FVIIa), plays a crucial role in cancer cell movement and inflammation.
  • Myeloid cells expressing FVII are important for recruiting inflammatory cells to the lungs after viral challenges, highlighting that a specific PAR2 cleavage pathway is essential for lung inflammation.
  • The study reveals that through biased signaling involving β-arrestin, PAR2 mediates macrophage migration and immune recruitment to lung tissues, suggesting that targeting this signaling pathway could offer new treatment options for inflammation-related conditions.
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  • The study aimed to assess the effectiveness of nurse-led interventions for individuals with dementia, focusing on their impact on cognitive function, depression, and quality of life.
  • A thorough search of literature revealed that nurse-led interventions significantly reduced depression and enhanced quality of life compared to standard care, but did not improve cognitive performance.
  • The findings highlight the success of nurse-led interventions in addressing emotional and quality-of-life issues in dementia care, yet indicate a need for more randomized controlled trials to fully understand their impact on cognitive function.
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The basal heave stability of supported excavations is an essential problem in geotechnical engineering. This paper considers the probabilistic analysis of basal heave stability of supported excavations with spatially random soils by employing the random adaptive finite element limit analysis and Monte Carlo simulations to simulate all possible outcomes under parametric uncertainty. The effect of soil strength variability is investigated for various parameters, including the width and depth of the excavation ratio, strength gradient factor, and vertical correlation length.

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Background: The cytogenetic characteristics are important factors for risk stratification at diagnosis of acute myeloid leukemia (AML); however, cytogenetic profile of Vietnamese patients with AML remains undetermined. In this study, we present the chromosomal data of de novo AML patients in Southern Vietnam.

Methods: We performed cytogenetic testing for 336 AML patients using G banding.

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Hipposideros larvatus sensu lato constitutes a widespread species complex consisting of morphologically similar forms with a taxonomy that is in need of a revision. Here we present the results of a phylogenetic analysis of members of this species complex based on two mitochondrial (CytB and COI) and seven nuclear (ABHD11, ACOX2, COPS, RAG2, ROGDI2, SORBS2 and THY) genes, and a morphometric analysis. Morphological data, although showing certain diversity, does not allow an accurate delimitation of the taxonomic boundaries and occasionally contradict to genetic grouping.

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Background: Patients with cancer who are not well informed often experience dissatisfaction with care, difficulty coping with their disease, and feelings of helplessness.

Purpose: This study was designed to investigate the information needs of women with breast cancer undergoing treatment in Vietnam and the determinants of these needs.

Methods: One hundred thirty women undergoing chemotherapy for breast cancer in the National Cancer Hospital in Vietnam enrolled as volunteers in this cross-sectional descriptive correlational study.

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Based on recently collected material and records in the literature, 14 species of fiddler crabs (Crustacea: Ocypodidae: Gelasiminae) are reported from Vietnam. DNA barcoding analyses using the mitochondrial gene (cytochrome oxidase subunit I) was performed to identify examined materials and their precise distributional range. Thirteen species-level taxa are identified and, with the exception of and , have minimum interspcific divergences of at least 7.

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