Publications by authors named "Nguyen T Kien"

Article Synopsis
  • The study aimed to compare the clinical, radiological, and laboratory features of newly diagnosed smear-positive pulmonary tuberculosis in elderly patients (65+) versus younger patients in Vietnam.
  • Out of 183 patients analyzed, those aged 65 and older showed differences in symptoms and X-ray findings, with younger patients more likely to experience night sweats and cavitation lesions, while elderly patients experienced more muscle/joint pain and pulmonary fibrosis.
  • The research highlights the need for age-specific considerations in diagnosing and treating tuberculosis, indicating that tailored approaches could improve patient outcomes based on age-related differences.
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Objectives: To detect clusters of dengue hemorrhagic fever in an urbanized district of Hai Phong City, Vietnam using Poisson space-time retrospective and prospective analysis.

Methods: A cross-sectional and retrospective study analyzed dengue surveillance data in the period from January 01, 2018, to December 31, 2022. Spatial-temporal scanning statistics were performed using the free software SatScan v10.

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The study aims to explore the potential for transplacental transmission of SARS-CoV-2, focusing on its pathophysiology, placental defense mechanisms, and the clinical implications for maternal and neonatal health. A comprehensive review of the current literature was conducted, analyzing studies on SARS-CoV-2 infection in pregnancy, the expression of key viral receptors (ACE2 and TMPRSS2) in placental cells, and the immune responses involved in placental defense. The review also examined the clinical outcomes related to maternal and neonatal health, including adverse pregnancy outcomes and neonatal infection.

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Article Synopsis
  • The study aimed to identify how common infections are among Vietnamese children with gastrointestinal symptoms and what factors might increase their risk.
  • It involved 246 children under 16 who underwent testing, revealing that about 81.3% had an infection, with older children being at a higher risk and factors like poor hand hygiene contributing significantly.
  • Key findings indicate that children with infected had different symptoms and complications and that proper handwashing can notably lower the chances of getting infected.
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There have been many studies on the adverse effects of coronavirus disease 2019 (COVID-19) vaccines but the urinary incontinence after COVID-19 vaccination is rare. Here, we report an 8-year-old boy presented to outpatient department, Thai Binh University of Medicine Hospital, Thai Binh, Vietnam with complaints of urinary incontinence for the past 2 weeks, following the first dose of the messenger RNA vaccine. He had no other abnormalities in clinical and laboratory exams.

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NaGdF:Dy nanocrystals (NCs) have been synthesized using a precipitation technique. The structural characteristics and morphology of the materials were analyzed using X-ray diffraction patterns and scanning electron microscopy images, respectively. The photoluminescence excitation spectra, emission spectra and decay curves of all samples were recorded at room temperature.

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The development of nanocomposite photocatalysts with high photocatalytic activity, cost-effectiveness, a simple preparation process, and scalability for practical applications is of great interest. In this study, nanocomposites of TiO Degussa P25 nanoparticles/activated carbon (TiO/AC) were prepared at various mass ratios of (4:1), (3:2), (2:3), and (1:4) by a facile process involving manual mechanical pounding, ultrasonic-assisted mixing in an ethanol solution, paper filtration, and mild thermal annealing. The characterization methods included XRD, SEM-EDS, Raman, FTIR, XPS, and UV-Vis spectroscopies.

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The objective of this study is to determine the fibrin monomer reference intervals in healthy children. This cross-sectional study was conducted in the Hematology Department at Vietnam National Children's Hospital (April 2023 to March 2024). Children without prior history of clotting disorders or anticoagulants use hospitalized in preparation for orthopedic surgery or inguinal hernia surgery were enrolled in the study.

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This study attempted to improve the photocatalytic activity of zinc oxide (ZnO) semiconductors in the visible light region by introducing the co-doping of carbon (C) and tantalum (Ta) to ZnO (ZTC) using a simple hydrothermal method with the respective precursors. The obtained uniform ZTC nanoparticles with an average crystal size of 29.30 nm (according to Scherrer's equation) revealed a redshift with a decrease in bandgap () from 3.

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Aim: To determine the dry eye (DE) rate and its relationship with disease stage in patients with primary hypertension.

Methods: A cross-sectional study included 432 patients with primary hypertension (with an equal number of patients in each group: 144 in stage I, II, and III hypertension) and 144 healthy subjects as a control group. The Ocular Surface Disease Index (OSDI) and Schirmer I test without anesthetics were conducted on all 576 subjects.

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Background: Hyperactive coagulation might cause dangerous complications such as portal vein thrombosis and pulmonary embolism after mesenchymal stem/stromal cell (MSC) therapy. Tissue factor (TF), an initiator of the extrinsic coagulation pathway, has been suggested as a predictor of this process.

Methods: The expression of TF and other pro- and anticoagulant genes was analyzed in xeno- and serum-free manufactured MSCs.

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Purpose: Our goal was to evaluate the neutrophil:lymphocyte (NLR) and platelet:lymphocyte (PLR) ratios measured before transplantation and their correlation with new-onset diabetes after transplantation (NODAT) in renal transplant recipients.

Patients And Methods: We conducted our study in 324 adult patients consecutively admitted to Military Hospital 103, Ha Noi, Viet Nam, who received kidney allografts from living donors. These patients were followed-up during the first 2 years post-transplantation for NODAT.

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Background: Familial hypercholesterolemia (FH) is an inherited metabolic disorder characterized by high levels of low-density lipoprotein cholesterol (LDL-c) from birth. About 85% of all FH cases are caused by pathogenic variants in the LDLR gene. Individuals with FH have increased cardiovascular risk, including a high risk of premature myocardial infarction (PMI).

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Introduction: Hypertension, a major health concern, is associated with significant mortality and disease burden worldwide, including Vietnam. Comprehensive interventions targeting medication, lifestyle modifications, dyslipidemia (DLP), and microalbuminuria (MAU) are vital for effective hypertension management and reducing the risk of cardiovascular disease complications (CDV). While medication interventions have proven efficacy, the evidence regarding the effectiveness of community-based health education interventions in managing DLP and MAU is limited.

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The adsorption process of inorganic arsenic (As) plays an important role in its mobility, bioavailability, and toxicity in the river environment. In this work, the adsorption of dissolved arsenite (As(III)) and arsenate (As(V)) by microplastics (MPs) pellets (polystyrene (PS) and low-density polyethylene (LDPE)), river sediment, and their mixture were investigated to assess the adsorption affinities and mechanism. The adsorption kinetics showed slow and mild rising zones from the natural behavior of the chemical adsorption.

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Introduction: Chronic low-grade inflammation (LGI) plays a role in the pathogenesis of gestational diabetes mellitus (GDM). LGI, on the one hand, promotes insulin resistance and at the same time, affects fetal development. The study aimed to use clinically feasible means to evaluate the association between maternal LGI and maternal insulin resistance and fetal growth indices by ultrasound in the third trimester.

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Anaemia is a public health concern in developing nations, particularly among women of reproductive age. However, the present prevalence and recent trend in anaemia among this population are unclear. This systematic review aimed to evaluate the prevalence of anaemia among non-pregnant women in Vietnam.

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Background: Identification of HER2 protein overexpression and/or amplification of the gene are required to qualify breast cancer patients for HER2 targeted therapies. hybridization (ISH) assays that identify gene amplification function as a stand-alone test for determination of HER2 status and rely on the manual quantification of the number of genes and copies of chromosome 17 to determine amplification.

Methods: To assist pathologists, we have developed the uPath HER2 Dual ISH Image Analysis for Breast (uPath HER2 DISH IA) algorithm, as an adjunctive aid in the determination of gene status in breast cancer specimens.

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Introduction And Importance: No case has been reported regarding esophago-gastrectomy due to caustic chemicals in the literature.

Case Presentation: The first case was a 43-year-old woman with BMI 28.5.

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The disease caused by the SARS-Cov 2 virus has spread to most areas of the world with high rates of infection and deaths. Facing the complicated developments of the epidemic, clinical medical staff (CMS) are at risk of suffering psychological pressure. This study aimed to investigate the situation of anxiety, depression, and related factors affecting CMS during the COVID-19 pandemic at Dong Da General Hospital and Dong Anh General Hospital in Hanoi.

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Introduction And Importance: A very rare case with presence of both esophageal and gastric cancers raised questions on how to perform optimal surgery for such cases. To date, reports on experimental surgery strategies for these rare cases remained sparse in the literatures.

Case Presentation: A 61-year-old male patient having epigastric abdominal pain and swallowing difficulties for a month prior to the hospital.

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Silicon (Si), as the second most abundant element on Earth, has been a central platform of modern electronics owing to its low mass density and unique semiconductor properties. From an energy perspective, all-in-one integration of power supply systems onto Si-based functional devices is highly desirable, which inspires significant study on Si-based energy storage. Compared to the well-known Si-anode Li-ion batteries, Si-based supercapacitors possess high power density, long life, and simple working mechanisms, which enables their ease of integration onto a wide range of devices and applications.

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Cyanobacteria are photosynthetic microorganisms with widespread diversity and extensive global distribution. They produce a wide variety of bioactive substances (e.g.

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Background: This study aims to determine the ratio of delayed graft function in renal transplant recipients from living donors and the predictive value of hemodialysis time before transplant for delayed graft function.

Methods: We conducted a study on 116 adult patients who were diagnosed with end-stage kidney disease and were treated with hemodialysis and transplanted kidneys from living donors for 2 years (from June 2018 to June 2020). Delayed graft function event was collected for each patient.

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Background: Pneumoperitoneum and Trendelenburg position in laparoscopic surgeries could contribute to postoperative pulmonary dysfunction. In recent years, intraoperative lung-protective mechanical ventilation (LPV) has been reportedly able to attenuate ventilator-induced lung injuries (VILI). Our objectives were to test the hypothesis that LPV could improve intraoperative oxygenation function, pulmonary mechanics and early postoperative atelectasis in laparoscopic surgeries.

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