Recycling paper sludge into hydrochar and ZnO nanocomposite for enhanced ammonium adsorption in aqueous solutions.

This study investigates the ammonium (NH ) adsorption capabilities of hydrochar derived from paper waste sludge (PWSH) and its modified variant with ZnO (PWSH@ZnO).This study investigates the ammonium (NH ) adsorption capabilities of hydrochar derived from paper waste sludge (PWSH) and its modified variant with ZnO (PWSH@ZnO). The adsorption behaviors were analyzed by varying parameters such as pH, contact time, initial NH concentration, and ZnO modification ratios.

Substrate system outperforms water-culture systems for hydroponic strawberry production.

Strawberries () are a globally cultivated fruit crop known for their economic significance and versatility in both fresh markets and processed food industries. Their high consumer demand and market value contribute to substantial profitability for producers. In recent years, due to increasing costs of production and occurrence of extreme weather events, the use of controlled environment agriculture (CEA) and hydroponics for strawberry production has become popular in several Asian, European, and American countries.

Activation of CAMK2 by pseudokinase PEAK1 represents a targetable pathway in triple negative breast cancer.

The PEAK family of pseudokinases, comprising PEAK1-3, play oncogenic roles in several poor prognosis human cancers, including triple negative breast cancer (TNBC). However, therapeutic targeting of pseudokinases is challenging due to their lack of catalytic activity. To address this, we screen for PEAK1 effectors and identify calcium/calmodulin-dependent protein kinase 2 (CAMK2)D and CAMK2G.

Prospective validation study: a non-invasive circulating tumor DNA-based assay for simultaneous early detection of multiple cancers in asymptomatic adults.

Background: Non-invasive multi-cancer early detection (MCED) tests have shown promise in enhancing early cancer detection. However, their clinical utility across diverse populations remains underexplored, limiting their routine implementation. This study aims to validate the clinical utility of a multimodal non-invasive circulating tumor DNA (ctDNA)-based MCED test, SPOT-MAS (Screening for the Presence Of Tumor by DNA Methylation And Size).

Sensor-controlled fertigation management for higher yield and quality in greenhouse hydroponic strawberries.

Controlled environment agriculture (CEA) for strawberry () production has experienced a growth in popularity in recent years, particularly in North America. One of the most common growing systems in CEA strawberry production is the soilless hydroponic system, which uses an inert substrate and nutrient solution to grow the plants. There are several strategies for water management in substrates, and most are based on a rigid schedule rather than variable plant water requirements over time.

Activating PKC-ε induces HIV expression with improved tolerability.

Despite suppressive antiretroviral therapy (ART), HIV-1 persists in latent reservoirs that seed new HIV infections if ART is interrupted, necessitating lifelong therapy for people with HIV. Activation of latent HIV during ART could improve recognition and elimination of infected cells by the immune system. Protein kinase C (PKC) isozymes increase HIV transcription and hence are potential latency reversal agents.

Cyanide Functionalization and Oxygen Vacancy Creation in Ni-Fe Nano Petals Sprinkled with MIL-88A Derived Metal Oxide Nano Droplets for Bifunctional Alkaline Seawater Electrolysis.

This work investigates novel improvements in FeNi-layered double hydroxide (LDH)/MIL-88A heterocomposite for sustainable seawater electrolysis through a single-step dual functionalization process. The Fe/Ni precursor weight ratio is optimized, resulting in the formation of smaller LDH petals and nano-sized MIL-88A metal-organic framework, which transforms into clusters of FeO nanospheres within a nitrogen-functionalized carbon matrix over NiFeO nano petals upon calcination. Furthermore, oxygen vacancies, and nitrogen functionalization are attained in a single step by employing thermal ammonia reduction, significantly improving the oxygen evolution reaction (OER) and hydrogen evolution reaction (HER) activities.

Vietnamese religiosity, premarital sexual permissiveness, and abortion attitudes: the mediating role of filial piety.

This study focuses on filial piety, a fundamental psychological factor in Vietnam and its relationship with religiosity and attitudes toward abortion. Drawing on data from 656 participants, the research employed the Partial Least Squares-Structural Equation Modeling (PLS-SEM) method and identified significant differences in intrinsic religiosity (IR) based on various forms of cohabitation with parents. Furthermore, the findings revealed a positive association between age and religiosity.

Combining Fundamental Kinetics and Standard Alkylation Assays to Prioritize Lead-Like KRAS G12C Inhibitors.

We measure the fundamental rate constants of internally discovered KRAS G12C inhibitors to demonstrate how kinetic analyses can be integrated with standard biochemical and cell-based assays for more optimal biophysical compound prioritization. In this proof-of-principle study, we characterize three irreversible covalent inhibitors targeting the mutant cysteine at the switch II binding pocket. We estimate the three fundamental kinetic rate constants ( , , ) that define the contributions of affinity and inactivation to the overall alkylation rate for a more complete biophysical characterization.

Dataset on ITS and some chloroplast DNA regions of Blume in Vietnam.

Species of the genus have the potential to be natural medicines and have industrial fibre production uses. Many species of this genus are morphologically similar and are difficult to distinguish, especially when their morphology is distorted. This dataset includes sequence information of several DNA regions isolated from the genome of , namely ITS (from the nuclear genome), , trnL-trnF, trnH-psbA, and (from the chloroplast genome) and phylogenetic analysis results based on the isolated sequences.

The Dynamic and Heterogeneous Effects of COVID-19 Vaccination Mandates in the USA.

Mandatory vaccination for COVID-19 has received intense political and ethical debates, while the literature on the causal effects of vaccination mandates on vaccination outcomes is very limited. In this study, we examine the effects of the announcement of vaccine mandates (VMs) for workers working in three sectors, including health, education, and state governments, on the uptake of first-dose and second-dose vaccination across 50 states in the United States of America. We show that VM announcements have heterogeneous effects; hence, standard two-way fixed effects and difference-in-differences estimators are biased.

Levofloxacin for the Prevention of Multidrug-Resistant Tuberculosis in Vietnam.

Background: Prevention of drug-resistant tuberculosis is a global health priority. However, trials evaluating the effectiveness of treating infection among contacts of persons with drug-resistant tuberculosis are lacking.

Methods: We conducted a double-blind, randomized, controlled trial comparing 6 months of daily levofloxacin (weight-based doses) with placebo to treat infection.

Three Novel Pathogenic Variants in Unrelated Vietnamese Patients with Cardiomyopathy.

: Cardiomyopathy, including dilated cardiomyopathy (DCM) and hypertrophic cardiomyopathy (HCM), is a major cause of heart failure (HF) and a leading indication for heart transplantation. Of these patients, 20-50% have a genetic cause, so understanding the genetic basis of cardiomyopathy will provide knowledge about the pathogenesis of the disease for diagnosis, treatment, prevention, and genetic counseling for families. : This study collected nine patients from different Vietnamese families for genetic analysis at The Cardiovascular Center, E Hospital, Hanoi, Vietnam.

Origins and developmental paths of medical conditions from mid-childhood to mid-adolescence in Australia: Early-life adverse conditions and their lasting effects.

This study investigates various common medical conditions affecting Australian children aged 4-14 years and the impact of prenatal and early-life conditions on these health conditions using a large national data set (n = 4122) with 15 years of follow-up. Consistent with the developmental origins of health and diseases hypothesis and the life-course models of health, the environment and parental financial hardship during pregnancy and shortly after birth play a significant role and have a lasting impact on the medical conditions of children. These significant effects are not reduced by controlling for child, family, and neighbourhood characteristics.

The effect of central and peripheral luminance on visual acuity.

Context: Lighting conditions significantly influence visual acuity (VA), visual function, and quality of life. Previous research highlighted a correlation between luminance and VA but left a gap in understanding the impact of surrounding luminance. This study focused on investigating the effects of both central and peripheral luminance on VA.

Efficacy of High Flow Nasal Cannula in the Treatment of Patients with COVID-19 with Acute Respiratory Distress Syndrome: Results of Single Centre Study in Vietnam.

Introduction: Most hospitalized patients required invasive or non-invasive ventilation and High Flow Nasal Cannula (HFNC). Therefore, this study was conducted to describe the characteristics of patients with severe Coronavirus Disease-2019 (COVID-19) treated by HFNC and its effectiveness for reducing the rate of intubated-mechanical ventilation in the Intensive Care Unit (ICU) of Phu Chanh COVID-19 Department-Binh Duong General Hospital.

Methods: It was a cross-sectional and descriptive study.

Sugarcane bagasse-derived biochar modified by alkali for enriching surface functional groups to effectively treat ammonium-contaminated water.

In this study, sugarcane bagasse (SB), which was preliminarily treated with HPO, was utilized to produce biochar (SB-BC). The SB-BC was subsequently modified with KOH to enrich oxygen-containing functional groups (OCFGs) for the enhanced adsorption of NH from wastewater. Batch tests revealed that KOH-modified SB-BC (SB-MBC) increased the maximum Langmuir adsorption capacity of NH by approximately twofold, from 27.

Optimization of PET depolymerization for enhanced terephthalic acid recovery from commercial PET and post consumer PET-bottles via low-temperature alkaline hydrolysis.

The increasing demand for plastic has resulted in a surge in plastic waste production. Polyethylene terephthalate (PET), commonly used in beverage bottle manufacturing, is only partially recycled, with an estimated recycling rate of just 28.4% in 2019.

A consultation and work-up diagnosis protocol for a multicancer early detection test: a case series study.

The emergence of multicancer early detection (MCED) tests holds promise for improving early cancer detection and public health outcomes. However, positive MCED test results require confirmation through recommended cancer diagnostic imaging modalities. To address these challenges, we have developed a consultation and work-up protocol for definitive diagnostic results post MCED testing, named SPOT-MAS.

Rifampicin tolerance and growth fitness among isoniazid-resistant clinical isolates from a longitudinal study.

Antibiotic tolerance in reduces bacterial killing, worsens treatment outcomes, and contributes to resistance. We studied rifampicin tolerance in isolates with or without isoniazid resistance (IR). Using a minimum duration of killing assay, we measured rifampicin survival in isoniazid-susceptible (IS, n=119) and resistant (IR, n=84) isolates, correlating tolerance with bacterial growth, rifampicin minimum inhibitory concentrations (MICs), and isoniazid-resistant mutations.

Lipid Composition, Cytotoxic and Acetylcholinesterase Inhibition Effects of Two Brown Algae Species Lobophora tsengii and Lobophora australis.

In this paper, the lipid classes, compositions of the neutral lipids, phospholipids and fatty acids, acetylcholinesterase inhibition and cytotoxic activity of two brown algae Lobophora tsengii D. Tien & Z. Sun and Lobophora australis Z.

A Non-Hemadsorbing Live-Attenuated Virus Vaccine Candidate Protects Pigs against the Contemporary Pandemic Genotype II African Swine Fever Virus.

African swine fever (ASF) is a highly contagious and severe hemorrhagic transboundary swine viral disease with up to a 100% mortality rate, which leads to a tremendous socio-economic loss worldwide. The lack of safe and efficacious ASF vaccines is the greatest challenge in the prevention and control of ASF. In this study, we generated a safe and effective live-attenuated virus (LAV) vaccine candidate VNUA-ASFV-LAVL3 by serially passaging a virulent genotype II strain (VNUA-ASFV-L2) in an immortalized porcine alveolar macrophage cell line (3D4/21, 50 passages).