Publications by authors named "Nguyen Khoi Le"
A functional genomics screen identifying blood cell development genes in Drosophila by undergraduates participating in a course-based research experience.
Cory J Evans John M Olson Bama Charan Mondal Pratyush Kandimalla Ariano Abbasi Elitzander Alegria-Leal Kai Y Alexander Alex W Chan Alexander J Chassiakos Rachel S Distler Leah C Dorman Alexander M Grunfeld Ashley Hanson Celesti Hao Ashley C Hope Eileen Hu Caleb Kim Nguyen Khoi Le Chi Ju Lee Dana Lee Dong Yeon Lee James Lee Jason Lee Jessica Lee Ju-Yeon Lee Sharon Lee Terrence C Lee Victoria Lee Alexandra M Libro David A Sanville Gabrielle Sibal Alexander Zai Alexis Baranoff Alec Estrada Ceejay Lee Grace Lee Jonelle Mungcal Sang Kuk Lee Olivia Lee Kyle Marik Marc Levis-Fitzgerald Leslie Jaworski
G3 (Bethesda)
January 2021
Article Synopsis
- - Undergraduate students at UCLA conducted research using RNA interference (RNAi) and fluorescent proteins to pinpoint genes crucial for blood cell development in fruit flies, screening around 3,500 genes and finding 137 that affected hematopoiesis.
- - By targeting RNAi to different cell types involved in blood cell maturation, the researchers identified specific gene subsets that either facilitate or inhibit this process, revealing new insights into gene functions related to RNA processing and vesicular trafficking.
- - The CURE (Course-Based Undergraduate Research Experience) model not only enhanced students' understanding and skills in science but also improved retention rates in STEM fields, demonstrating the value of hands-on research in education.