Supercritical CO assisted extraction of essential oil and naringin from peel: antimicrobial activity and docking study.

The extraction of bioactive compounds, including essential oils and flavonoids, using organic solvents is a significant environmental concern. In this work, waste peel was the ingredient used to extract essential oil and naringin by conducting a supercritical CO technique with a two stage process. In the first stage, the extraction with only supercritical CO solvent showed a significant enhancement of the d-limonene component, up to 95.