Determinants of antibiotic prescribing in primary care in Vietnam: a qualitative study using the Theoretical Domains Framework.

Background: To formulate effective strategies for antimicrobial stewardship (AMS) in primary care, it is crucial to gain a thorough understanding of factors influencing prescribers' behavior within the context. This qualitative study utilizes the Theoretical Domains Framework (TDF) to uncover these influential factors.

Methods: We conducted a qualitative study using in-depth interviews and focus group discussions with primary care workers in two provinces in rural Vietnam.

Genome-wide expression analysis in a Fabry disease human podocyte cell line.

Fabry disease (FD) is an X-linked lysosomal disease caused by an enzyme deficiency of alpha-galactosidase A (α-gal A). This deficiency leads to the accumulation of glycosphingolipids in lysosomes, resulting in a range of clinical symptoms. The complex pathogenesis of FD involves lysosomal dysfunction, altered autophagy, and mitochondrial abnormalities.

LiOBu-promoted synthesis of bis(3-indolyl)methanes by the alkylation of indoles with alcohols under air.

Bis(3-indolyl)methanes (BIMs) are known for their important bioactivities, which include anti-cancer, anti-inflammatory, antibacterial, and antioxidant properties. In this study, we are disclosing a metal catalyst-free synthesis of BIMs in high yields the alkylation reaction of indoles and alcohols in the presence of lithium -butoxide base. Notably, oxygen in air played an important role as an oxidant for the facilitation of this transformation.

Untargeted Metabolomics Approach for the Differentiation between var. and var. .

var. (PVV) and var. (PVF) both belong to species and are chemically and morphologically similar, making it hard to distinguish for the consumer.

Factors affecting need for blood transfusion in paediatric patients undergoing open surgery for hip dysplasia.

Background And Objectives: The management of intraoperative blood loss in the surgical treatment of paediatric hip dysplasia is resource intensive. There are numerous clinical factors that impact the need for intraoperative transfusion. Identification of patient and surgical factors associated with increased blood loss may reduce the unnecessary use of resources.

Influence of Additional Micro-Sized Particles of Dy-Nd-Cu-Al on Magnetic Properties of Sintered Nd-Fe-B Magnets.

In this work, we investigated the influence of concentration of the additional micro-sized particles of DyNdAl and NdCuAl on magnetic properties of the sintered NdFeB magnets. The additional particles with size in the range of 1-3 m were prepared by ball milling method and then mixed into micrometer NdFeB master powder with different weight fractions before magnetic anisotropic pressing, vacuum sintering and annealing. The results show that the coercivity of the sintered Nd-Fe-B magnets can be improved considerably by introducing additional particles to the grain boundaries.

Influence of Co-Doping on Magnetic Properties and Magnetocaloric Effect of Fe-Co-Zr-Cu-B Melt-Spun Ribbons.

In this work, we investigated magnetic properties and magnetocaloric effect in FeCoZrCuB₂ ( = 0, 1, 2, 3 and 4) melt-spun ribbons. The ribbons were prepared by using a melt-spinning method with a tangential velocity of a copper wheel of 40 m·s. The obtained ribbons are almost amorphous.

Does it match? Analyzing self-reported online dermatology match data to Charting Outcomes in the Match.

Dermatology is arguably the most competitive residency (81.6% match rate for United States allopathic seniors) with significantly more applicants than available positions. To objectify this process, the National Residency Match Program (NRMP) has produced bi-annual Charting Outcomes in Match (COM) datasets, which aggregate data from the prior two application cycles and tabulate statistics to aid applicants.

Determining the density of liquid using gamma scattering method.

This study proposes an approach to determine the density of a liquid based on the gamma scattering method. The liquids used to determine density were poured in a cylindrical tube. This approach requires that the ratio R (the ratio of area under a single scattering peak for a liquid to that for water) increase linearly with an increase in the density of the liquid.

One-pot synthesis of manganese oxide/graphene composites via a plasma-enhanced electrochemical exfoliation process for supercapacitors.

In this work, a feasible one-pot approach to synthesize manganese oxide/graphene composites, the so-called plasma-enhanced electrochemical exfoliation process (PEP), has been developed. Herein, a composite of graphene decorated with manganese oxide nanoparticles was prepared via PEP from a KMnO solution and graphite electrode under a voltage of 70 V in an ambient environment. By controlling the initial KMnO concentration, we obtained distinct MnO/graphene samples.

Optimization of the Monte Carlo simulation model of NaI(Tl) detector by Geant4 code.

This work aimed to optimize the Monte Carlo simulation model of NaI(Tl) detector by Geant4 code. For detector modeling, the geometrical parameters are usually derived from the manufacturer's specification because of availability and convenience. However, the difference between real and nominal values in geometrical parameters of the detector can considerably affect the simulation results.

Prospecting for Energy-Rich Renewable Raw Materials: Sorghum Stem Case Study.

Sorghum vegetative tissues are becoming increasingly important for biofuel production. The composition of sorghum stem tissues is influenced by genotype, environment and photoperiod sensitivity, and varies widely between varieties and also between different stem tissues (outer rind vs inner pith). Here, the amount of cellulose, (1,3;1,4)-β-glucan, arabinose and xylose in the stems of twelve diverse sorghum varieties, including four photoperiod-sensitive varieties, was measured.

Characteristics of participants in peripartum interventional research.

Objective: To identify characteristics of pregnant women potentially influencing the decision to participate in peripartum interventional research.

Methods: Women screened as eligible to participate in two prospective interventional trials conducted in the labor and delivery unit at a single center were included. Characteristics of eligible women were compared based on their decision whether to participate or not.

The location of asparagine-linked glycans on West Nile virions controls their interactions with CD209 (dendritic cell-specific ICAM-3 grabbing nonintegrin).

Mammalian cell-derived West Nile virus preferentially infects cells expressing the C-type lectin CD209L (dendritic cellspecific ICAM-3 grabbing nonintegrin-related protein; liver- and lymph node-specific ICAM-3 grabbing nonintegrin) but not cells expressing CD209 (dendritic cell-specific ICAM-3 grabbing nonintegrin). In contrast, Dengue virus infection is enhanced in cells expressing either attachment factor. The West Nile virus envelope (E) protein contains a single N-linked glycosylation site at residue 154, whereas Dengue virus E contains sites at residues 153 and 67.

West Nile virus discriminates between DC-SIGN and DC-SIGNR for cellular attachment and infection.

The C-type lectins DC-SIGN and DC-SIGNR bind mannose-rich glycans with high affinity. In vitro, cells expressing these attachment factors efficiently capture, and are infected by, a diverse array of appropriately glycosylated pathogens, including dengue virus. In this study, we investigated whether these lectins could enhance cellular infection by West Nile virus (WNV), a mosquito-borne flavivirus related to dengue virus.