Publications by authors named "Ngoc Bao Tran"

This research aims to develop bitter taste-masking microcapsules containing azithromycin (AZI) by a simpler and familiar method, fluid-bed coating technology, in comparison with Zithromax. Cores of microcapsules, AZI microparticles, were prepared by fluid-bed granulation, then taste-masking polymer was covered on by fluid-bed coating technique. Eudragit L100, Eudragit RL100, and ethyl cellulose in single and combined with Eudragit L100 and Eudragit E100 were used as taste-masking polymers.

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Herein, we report a solid-state lithography technique utilizing eutectic friction transfer lithography (EFTL). The EFTL technique employs eutectic pellets made of semiconducting polymers and volatile organic solid matrices. Using frictional heating and eutectic melting, various semiconducting polymer crystals were formed by a simple rubbing process under mild conditions.

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There have been many strategies to increase solubility, dissolution rates, and oral bioavailability of fenofibrate such as micronization, nanonization, solid dispersion, and emulsion so far. To our knowledge, only first three technologies have been applied in producing marketed products, and no combination of solid dispersion and pellet has been found even in laboratory-based reports. Therefore, the aim of this study was to develop novel solid dispersion-based pellets via an one-step process directly from fenofibrate powder using layering method.

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