Two New Steroidal Saponins with Potential Anti-Inflammatory Effects from the Aerial Parts of Markgr.

Markgr., a member of the Gnetaceae family, is distributed in Vietnam. This plant remains a botanical enigma with an unexplored diversity of chemical constituents and pharmacological effects.

Withaperuvin O, a new withanolide from L.

L. (Solanaceae) has been used in tropical and subtropical countries of the world as medicinal and fruit trees. In this study, a new withanolide named withaperuvin O () and seven known ones, including physalolactone B-3-O--D-glucopyranoside (), withanolide J (), physapruin A (), physaperuvin G (), withaperuvin (), withaperuvin C () and 28-hydroxywithaperuvin C (), were isolated from the whole plants of .

Alpha-Glucosidase Inhibitory Activity of Saponins Isolated from Hance.

Species belonging to the (Asteraceae), the largest genus in the tribe Vernonieae (consisting of about 1,000 species), are widely used in food and medicine. These plants are rich sources of bioactive sesquiterpene lactones and steroid saponins, likely including many as yet undiscovered chemical components. A phytochemical investigation resulted in the separation of three new stigmastane-type steroidal saponins (1 - 3), designated as vernogratiosides A-C, from whole plants of .

Isolation, structural elucidation and molecular docking studies against SARS-CoV-2 main protease of new stigmastane-type steroidal glucosides isolated from the whole plants of .

Phytochemical investigation of the whole plants of Hance. led in the isolation and identification of two new stigmastane-type steroidal glucosides (-), namely vernogratiosides A (), and B (). Their chemical structures were fully elucidated based on 1 D/2D NMR spectroscopic, HR-ESI-MS data analyses, and by producing derivatives by chemical reactions.

Inhibitory Effects of Cucurbitane-Type Triterpenoids from Fruit on Lipopolysaccharide-Stimulated Pro-Inflammatory Cytokine Production in Bone Marrow-Derived Dendritic Cells.

The bitter melon, L., was once an important food and medicinal herb. Various studies have focused on the potential treatment of stomach disease with .

Anti-inflammatory secondary metabolites from the stems of Millettia dielsiana Harms ex Diels.

A phytochemical investigation for the constituents of the stems of Millettia dielsiana Harms ex Diels resulted in the isolation of a new isoflavone glycoside, mildiside A (1), and 14 known compounds (2-15). Their chemical structures were determined using a combination of IR, NMR, MS, and optical rotation analysis, as well as comparison with the literature data. The ethanolic (EtOH) extract and several isolated compounds exert the inflammatory effect of nitric oxide (NO) production in lipopolysaccharide (LPS)-stimulated murine RAW264.

Estimation of functional components of Chinese cabbage leaves grown in a plant factory using diffuse reflectance spectroscopy.

Background: In recent years, protected crop production using plant factories to produce high-value crops with greater functional components has become more popular in many countries. The quantification of the components, however, is mainly conducted by laboratory analyses, which are both time- and labor-consuming. The present study aimed to investigate the potential of a non-destructive diffuse reflectance spectroscopy technique for estimating functional components (i.