Publications by authors named "Nghia Quang Huy Hoang"
Cytotoxic effects of the standardized extract from Salisb. rhizomes via induction of mitochondria-mediated caspase-dependent apoptotic pathway and p21-mediated G0/G1 cell cycle arrest on human gastric cancer AGS cells.
Chinh Chung Doan Thanh Long Le Nguyen Quynh Chi Ho Thi Thuy Nguyen Nghia Quang Huy Hoang Nghia Son Hoang
J Toxicol Environ Health A
December 2024
Article Synopsis
- Salisb. is a traditional herb used to treat various diseases, including gastric cancer, but its specific effects on gastric cancer cells require further investigation.
- This study explored how a standardized extract of Salisb. rhizome induces cell death in gastric cancer AGS cells, primarily through apoptosis and cell cycle disruption.
- The extract's active compounds, curdione and germacrone, were shown to affect mitochondrial function and cell cycle regulatory proteins, highlighting their potential as anti-cancer agents.